Evidence map›Paper›PMID 38685017›Full record

Observational studyBMC health services research2024

Exploring patients' perspectives: a mixed methods study on Outpatient Parenteral Antimicrobial Therapy (OPAT) experiences.

Sophie Peter, Charlotte Oberröhrmann, Holger Pfaff, Clara Lehmann, Kirsten Schmidt-Hellerau, Vanessa Brandes, Charlotte Leisse, Christoph Heinrich Lindemann, Peter Ihle, Jutta Küpper-Nybelen and 2 more

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC health services research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04002453 (Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04002453 unknown statusnot on this map

Outpatient Parenteral Antibiotic Therapy in the Metropolitan Area of Cologne

Typeobservational_patient_registrySponsorUniversity of CologneRan2020 to 2023Enrolled120ConditionsImplementation of OPAT in GermanyArmsOutpatient Parenteral Antibiotic Therapy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A bundle of the top 10 OPAT publications in 2024.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sophie PeterChair of General Practice II and Patient-Centredness in Primary Care, Institute of General Practice and Primary Care, Faculty of Health, Witten/Herdecke University, Witten, Germany. sophie.peter@uni-wh.de.
Charlotte OberröhrmannUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research and Rehabilitation Science, Chair of Health Services Research, Cologne, Germany.
Holger PfaffUniversity of Cologne, Faculty of Human Sciences and Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research and Rehabilitation Science Cologne, Cologne, Germany.
Clara LehmannDepartment I of Internal Medicine, Medical Faculty, University Hospital Cologne, University of Cologne, Cologne, Germany.
Kirsten Schmidt-HellerauDepartment I of Internal Medicine, Medical Faculty, University Hospital Cologne, University of Cologne, Cologne, Germany.
Vanessa BrandesDepartment I of Internal Medicine, Medical Faculty, University Hospital Cologne, University of Cologne, Cologne, Germany.
Charlotte LeisseDepartment I of Internal Medicine, Medical Faculty, University Hospital Cologne, University of Cologne, Cologne, Germany.
Christoph Heinrich LindemannDepartment II of Internal Medicine and Center for Molecular Medicine Cologne (CMMC),, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Peter IhlePMV forschungsgruppe, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Jutta Küpper-NybelenPMV forschungsgruppe, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Anna HagemeierInstitute of Medical Statistics and Computational Biology (IMSB), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Nadine ScholtenUniversity of Cologne, Faculty of Medicine and University Hospital Cologne, Institute of Medical Sociology, Health Services Research and Rehabilitation Science, Chair of Health Services Research, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutpatient Parenteral Antimicrobial Therapy (OPAT), an alternative to inpatient intravenous antibiotic therapy, has shown benefits in international studies such as increased patient satisfaction. Because OPAT has been used only sporadically in Germany so far, no structured results on patients' experiences and concerns regarding OPAT have yet been available. This study therefore aims to explore the experiences of OPAT patients in a pilot region in Germany.

methodsThis is an observational study in a German pilot region, including a survey of 58 patients on their experiences with OPAT, and in-depth interviews with 12 patients (explanatory-sequential mixed-methods design).

resultsPatients reported that they were satisfied with OPAT. That a hospital discharge was possible and anti-infective therapy could be continued in the home environment was rated as being particularly positive. In the beginning, many patients in the interviews were unsure about being able to administer the antibiotic therapy at home on their own. However, healthcare providers (doctors and pharmacy service provider staff) were able to allay these concerns. Patients appreciated regular contact with care providers. There were suggestions for improvement, particularly concerning the organization of the weekly check-up appointments and the provision of information about OPAT.

conclusionsPatients were generally satisfied with OPAT. However, the treatment structures in Germany still need to be expanded to ensure comprehensive and high-quality OPAT care.

trial registrationNCT04002453, https://www. CLINICALTRIALS: gov/ , (registration date: 2019-06-21).

Indexed as

Ambulatory CarePatient SatisfactionAdultAgedAged, 80 and overAnti-Bacterial AgentsAnti-Infective AgentsFemaleGermanyHumansInfusions, ParenteralInterviews as TopicMaleMiddle AgedPilot ProjectsQualitative ResearchAnti-Bacterial AgentsAnti-Infective AgentsBacterial/viral infectionsIntravenous therapyOPATOutpatient Parenteral Antimicrobial TherapyPatient Reported Outcome MeasuresPatient satisfaction

Identifiers

PMID38685017
PMCPMC11057129

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.