Evidence map›Paper›PMID 38684993›Full record

SynthesisBMC pediatrics2024

The effect of vitamin D status on the occurrence of Kawasaki Disease: a meta-analysis.

Haixiang Zhang, Fuyong Jiao, Jiaojiao Wang, Cuixiang Xu, Kejin Zhang

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Vitamin D and Kawasaki disease.Frontiers in pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Haixiang ZhangShaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, 256# Youyi West Road, Xi'an, Shaanxi, 710068, China.
Fuyong JiaoShaanxi Provincial Kawasaki Disease Treatment Center/Children's Hospital of Shaanxi Provincial People's Hospital, Xi'an, 710068, China.
Jiaojiao WangShaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, 256# Youyi West Road, Xi'an, Shaanxi, 710068, China.
Cuixiang XuShaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, 256# Youyi West Road, Xi'an, Shaanxi, 710068, China. xucuixiang1129@163.com.
Kejin ZhangShaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, 256# Youyi West Road, Xi'an, Shaanxi, 710068, China. zhangkj@nwu.edu.cn.ORCID http://orcid.org/0000-0002-0820-3350
Shanxi Medical University · CNShaanxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe relationship between vitamin D status and Kawasaki Disease (KD), as well as coronary artery lesion (CAL), has yet to be established.

methodsA meta-analysis was conducted to assess the correlation between vitamin D status and KD, as well as the impact of vitamin D status on the progression of KD into CAL.

resultsThe meta-analysis revealed a consistent and significant association between serum 25(OH)D level and the occurrence KD (studies N = 22; z = -3.51, P < 0.001). Patients with KD had markedly lower levels of vitamin D than healthy controls (SMD: -1.30 ng/mL, 95%CI: -2.05 to -0.55 ng/mL).

conclusionThe study provided evidence supporting a significant association between lower serum vitamin D levels and the occurrence of KD, particularly within the Chinese population. However, the findings did not suggest a direct impact of vitamin D on the development of CAL in KD patients.

Indexed as

Mucocutaneous Lymph Node SyndromeVitamin DVitamin D DeficiencyCoronary Artery DiseaseDisease ProgressionHumansVitamin D25-hydroxyvitamin DCoronary artery lesionKawasaki diseaseVitamin D

Identifiers

PMID38684993
PMCPMC11057174
OpenAlexW4396229078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.