Evidence map›Paper›PMID 38684898›Full record

ReviewNature genetics2024

Advancing genomics to improve health equity.

Ebony B Madden, Lucia A Hindorff, Vence L Bonham, Tabia Henry Akintobi, Esteban G Burchard, Kellan E Baker, Rene L Begay, John D Carpten, Nancy J Cox, Valentina Di Francesco and 27 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Ebony B MaddenOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA. ebony.madden@nih.gov.ORCID http://orcid.org/0000-0003-4510-9563
Lucia A HindorffOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
Vence L BonhamOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
Tabia Henry AkintobiDepartment of Community Health and Preventative Medicine, Morehouse School of Medicine, Atlanta, GA, USA.
Esteban G BurchardDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0001-7475-2035
Kellan E BakerWhitman-Walker Institute, Washington, DC, USA.
Rene L BegayCenters for American Indian and Alaska Native Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
John D CarptenComprehensive Cancer Center, City of Hope, Duarte, CA, USA.
Nancy J CoxVanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
Valentina Di FrancescoOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.ORCID http://orcid.org/0009-0001-9208-5560
Denise A DillardDepartment of Medical Education and Clinical Sciences, Washington State University College of Medicine, Seattle, WA, USA.
Faith E FletcherCenter for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA.
Stephanie M FullertonDepartment of Bioethics and Humanities, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0938-6048
Nanibaa' A GarrisonInstitute for Society and Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-6228-3216
Catherine M Hammack-AviranDepartment of Health Policy, Vanderbilt University, Nashville, TN, USA.
Vanessa Y HiratsukaCenter for Human Development, University of Alaska Anchorage, Anchorage, AK, USA.ORCID http://orcid.org/0000-0002-4234-9441
James E K HildrethMeharry Medical College, Nashville, TN, USA.
Carol R HorowitzIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Chanita A Hughes HalbertDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
Michael InouyeDepartment of Public Health and Primary Care, University of Cambridge Victor Phillip Dahdaleh Heart and Lung Research Institute, Cambridge, UK.ORCID http://orcid.org/0000-0001-9413-6520
Amber JacksonOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
Latrice G LandryPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Rick A KittlesMorehouse School of Medicine, Atlanta, GA, USA.
Jeff T LeekFred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA.
Nita A LimdiDepartment of Neurology, University of Alabama, Birmingham School of Medicine, Birmingham, AL, USA.
Nicole C LockhartOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
Elizabeth O OfiliDepartment of Medicine, Morehouse School of Medicine, Atlanta, GA, USA.
Eliseo J Pérez-StableNational Institute on Minority Health and Health Disparities, Bethesda, MD, USA.
Maya SabatelloCenter for Precision Medicine and Genomics, Columbia University, New York, NY, USA.
Loren SaulsberryDepartment of Public Health Sciences, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0325-2329
Lorjetta E SchoolsCommon Fund, National Institutes of Health, Bethesda, MD, USA.
Jennifer L TroyerOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
Benjamin S WilfondDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
Genevieve L WojcikDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-7206-8088
Judy H ChoIcahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-7959-0466
Sandra S-J LeeDepartment of Medical Humanities and Ethics, Columbia University, New York, NY, USA.
Eric D GreenOffice of the Director, National Human Genome Research Institute, Bethesda, MD, USA.

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MONICA E PEEK · 2011 to 2026
$10.0M
Health Equity and Risk Communication in PharmacogenomicsK08HG011505 · NHGRI · UNIVERSITY OF CHICAGO · PI SAULSBERRY, LOREN · 2020 to 2024
$836k
Intramural NIH HHS Z99 HG999999NHGRI NIH HHS K08 HG011505NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

Health equity is the state in which everyone has fair and just opportunities to attain their highest level of health. The field of human genomics has fallen short in increasing health equity, largely because the diversity of the human population has been inadequately reflected among participants of genomics research. This lack of diversity leads to disparities that can have scientific and clinical consequences. Achieving health equity related to genomics will require greater effort in addressing inequities within the field. As part of the commitment of the National Human Genome Research Institute (NHGRI) to advancing health equity, it convened experts in genomics and health equity research to make recommendations and performed a review of current literature to identify the landscape of gaps and opportunities at the interface between human genomics and health equity research. This Perspective describes these findings and examines health equity within the context of human genomics and genomic medicine.

Indexed as

GenomicsHealth EquityGenome, HumanHumansNational Human Genome Research Institute (U.S.)United States

Identifiers

PMID38684898
PMCPMC11096049

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.