Evidence map›Paper›PMID 38684894›Full record

ArticleNature neuroscience2024

Abstract deliberation by visuomotor neurons in prefrontal cortex.

Julie A Charlton, Robbe L T Goris

Abstract read
In one paragraph

Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. The human language processing system straightens natural speech.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. No Central Executive? Decision Formation Through Multi-Area Population Dynamics.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  10. Brain-wide coordination of internal signals during decision-making.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Computational and Neuronal Basis of Visual Confidence.Annual review of vision science · 2025
    Review
  14. Sensory population activity reveals downstream confidence computations in the primate visual system.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Bayesian inference by visuomotor neurons in the prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Bayesian inference by visuomotor neurons in prefrontal cortex.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Julie A CharltonCenter for Perceptual Systems, The University of Texas at Austin, Austin, TX, USA.
Robbe L T GorisCenter for Perceptual Systems, The University of Texas at Austin, Austin, TX, USA. robbe.goris@utexas.edu.ORCID http://orcid.org/0000-0002-2218-3720

Funding

CPS Training ProgramT32EY021462 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI Mary M Hayhoe, Alexander C Huk · 2012 to 2026
$2.5M
Uncertainty, inference, and introspection in the primate visual systemR01EY032999 · NEI · UNIVERSITY OF TEXAS AT AUSTIN · PI GORIS, ROBBE L · 2022 to 2025
$1.6M
National Science Foundation (NSF) CAREER grant #2146369NEI NIH HHS R01 EY032999NEI NIH HHS T32 EY021462U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) EY032999U.S. Department of Health & Human Services | NIH | Office of Extramural Research, National Institutes of Health (OER) EY021462
6 · The paper itself

Abstract

During visually guided behavior, the prefrontal cortex plays a pivotal role in mapping sensory inputs onto appropriate motor plans. When the sensory input is ambiguous, this involves deliberation. It is not known whether the deliberation is implemented as a competition between possible stimulus interpretations or between possible motor plans. Here we study neural population activity in the prefrontal cortex of macaque monkeys trained to flexibly report perceptual judgments of ambiguous visual stimuli. We find that the population activity initially represents the formation of a perceptual choice before transitioning into the representation of the motor plan. Stimulus strength and prior expectations both bear on the formation of the perceptual choice, but not on the formation of the action plan. These results suggest that prefrontal circuits involved in action selection are also used for the deliberation of abstract propositions divorced from a specific motor plan, thus providing a crucial mechanism for abstract reasoning.

Indexed as

Macaca mulattaNeuronsPhotic StimulationPrefrontal CortexPsychomotor PerformanceAnimalsChoice BehaviorMaleVisual Perception

Identifiers

PMID38684894
PMCPMC11156582

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.