Evidence map›Paper›PMID 38684890›Full record

ArticleScientific reports2024

Efficient computational modeling of electronic stopping power of organic polymers for proton therapy optimization.

F Matias, T F Silva, N E Koval, J J N Pereira, P C G Antunes, P T D Siqueira, M H Tabacniks, H Yoriyaz, J M B Shorto, P L Grande

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

F MatiasInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil. phdflaviomatias@gmail.com.
T F SilvaInstituto de Física da Universidade de São Paulo, Rua do Matão, trav. R187, São Paulo, 05508-090, Brazil.
N E KovalCentro de Física de Materiales, Paseo Manuel de Lardizabal 5, Donostia-San Sebastián, 20018, Spain.
J J N PereiraInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil.
P C G AntunesInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil.
P T D SiqueiraInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil.
M H TabacniksInstituto de Física da Universidade de São Paulo, Rua do Matão, trav. R187, São Paulo, 05508-090, Brazil.
H YoriyazInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil.
J M B ShortoInstituto de Pesquisas Energéticas e Nucleares, Av. Professor Lineu Prestes, São Paulo, 05508-000, Brazil.
P L GrandeInstituto de Física da Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, Porto Alegre, 9500, Brazil.
Instituto de Pesquisas Energéticas e Nucleares · BRUniversidade de São Paulo · BRMaterial Physics Center · ESUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive study delves into the intricate interplay between protons and organic polymers, offering insights into proton therapy in cancer treatment. Focusing on the influence of the spatial electron density distribution on stopping power estimates, we employed real-time time-dependent density functional theory coupled with the Penn method. Surprisingly, the assumption of electron density homogeneity in polymers is fundamentally flawed, resulting in an overestimation of stopping power values at energies below 2 MeV. Moreover, the Bragg rule application in specific compounds exhibited significant deviations from experimental data around the stopping maximum, challenging established norms.

Identifiers

PMID38684890
PMCPMC11058815
OpenAlexW4396214666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.