Evidence map›Paper›PMID 38684815›Full record

Trial reportScientific reports2024

Switching diets after 6-months does not result in renewed weight loss: a secondary analysis of a 12-month crossover randomized trial.

Matthew J Landry, Catherine P Ward, Kristen M Cunanan, Priya Fielding-Singh, Anthony Crimarco, Christopher D Gardner

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Matthew J LandryStanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA, USA. matthew.landry@uci.edu.
Catherine P WardStanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA, USA.
Kristen M CunananQuantitative Science Unit, School of Medicine, Stanford University, Stanford, CA, USA.
Priya Fielding-SinghSandberg Goldberg Bernthal Family Foundation, San Francisco, CA, USA.
Anthony CrimarcoDivision of Gastroenterology and Hepatology, Stanford Center for Clinical Research, Stanford University, Redwood City, CA, USA.
Christopher D GardnerStanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA, USA.
Stanford Medicine · USStanford University · USSwiss National Science Foundation · CHUC Irvine Health · US

Funding

XOLAIR IN SUBJECTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS WITH FOOD ALLERGYM01RR000070 · NCRR · STANFORD UNIVERSITY · PI RASGON, NATALIE L · 1985 to 2008
$32.4M
CARDIOVASCULAR DISEASE PREVENTION TRAINING PROGRAMT32HL007034 · NHLBI · STANFORD UNIVERSITY · PI GARDNER, CHRISTOPHER D · 1985 to 2020
$8.7M
NCRR NIH HHS M01 RR000070NHLBI NIH HHS T32 HL007034NIH HHS T32HL007034
6 · The paper itself

Abstract

Weight change trajectory from diet and lifestyle interventions typically involves rapid weight loss followed by a weight plateau after approximately 6 months. Changing from one weight-loss diet to another at the time of the plateau could instigate renewed weight loss. Therefore, our secondary analysis aimed to assess trajectory of weight loss in a 12-month, randomized, cross-over study. Forty-two adults were randomized to eat a healthy low-fat or healthy low-carbohydrate diet for 6 months then switched to the opposite diet for an additional 6 months. Regardless of diet assignment, participants experienced rapid initial weight loss, which slowed between 3 to 6 months. After switching diets at 6 months, weight modestly decreased until 9 months, but at a rate slower than the initial 3 months and slower than the rate from 3 to 6 months. This suggests that the weight loss plateau typically seen at 6 months is physiological and cannot be overcome by simply switching to a different weight-loss diet.

Indexed as

Cross-Over StudiesWeight LossAdultDiet, Carbohydrate-RestrictedDiet, Fat-RestrictedDiet, ReducingFemaleHumansMaleMiddle AgedObesity

Identifiers

PMID38684815
PMCPMC11058757
OpenAlexW4396241922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.