Evidence map›Paper›PMID 38684621›Full record

ArticleArchives of sexual behavior2024

Risk Compensation After Initiation of Daily Oral Pre-exposure Prophylaxis Among Sexual and Gender Minorities in Nigeria.

Olusegun A Adeyemi, Rebecca G Nowak, Daniel Morgan, Nadia A Sam-Agudu, Jaih Craddock, Min Zhan, Trevor A Crowell, Stefan Baral, Sylvia Adebajo, Manhattan E Charurat and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of sexual behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olusegun A AdeyemiDepartment of Public Health and Epidemiology, University of Maryland School of Medicine, 725 West Lombard Street, S422, Baltimore, MD, 21201, USA. shegun.adeyemi230509@gmail.com.ORCID 0000-0002-2051-002X
Rebecca G NowakInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
Daniel MorganDepartment of Public Health and Epidemiology, University of Maryland School of Medicine, 725 West Lombard Street, S422, Baltimore, MD, 21201, USA.
Nadia A Sam-AguduInternational Research Center of Excellence, Institute of Human Virology Nigeria, Abuja, Nigeria.
Jaih CraddockSchool of Medicine, University of California, Irvine, CA, USA.
Min ZhanDivision of Biostatistics and Bioinformatics, Department of Public Health and Epidemiology, University of Maryland School of Medicine, Baltimore, MD, USA.
Trevor A CrowellHenry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Stefan BaralThe Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Sylvia AdebajoCenter for International Health, Education, and Biosecurity, Abuja, Nigeria.
Manhattan E CharuratInstitute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, USA.
TRUST/RV368 Study Group

Funding

Validation of Stigma Metrics for Marginalized Men R01MH110358 · NIMH · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2017 to 2021
$3.6M
Leveraging Big Data Science to Focus the HIV Response in Countries with Generalized HIV EpidemicsR01AI170249 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BARAL, STEFAN DAVID · 2022 to 2025
$2.9M
TRUSTR01MH099001 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2012 to 2014
$2.9M
Epidemiology Research Training for Public Health Impact in Nigeria (Epi-Nigeria)D43TW010051 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI ABIMIKU, ALASH'LE G., CHARURAT, MANHATTAN E · 2016 to 2020
$1.5M
FIC NIH HHS D43 TW010051FIC NIH HHS D43TW010051NIAID NIH HHS R01 AI170249NIMH NIH HHS R01 MH099001NIMH NIH HHS R01 MH110358
6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) use may be associated with risk compensation. We enrolled and provided PreP to sexual and gender minorities (SGM) in Abuja, Nigeria between April 2018 and May 2019. Behavioral information and samples for urogenital and anorectal Chlamydia trachomatis and Neisseria gonorrhoeae sexually transmitted infections (STIs) were collected at baseline. Blood samples for PrEP assay and self-reported adherence were collected at three-monthly follow-up visits. STIs were detected using Aptima Combo2 assay. We estimated the odds ratios (ORs) of PCR-diagnosed bacterial STIs and self-reported behavioral outcomes (condomless anal intercourse [CAI] and concurrent sexual relationships) with conditional logistic regression. Of 400 SGM who initiated PrEP, 206 were eligible for analysis, and had a median age of 24 years (IQR 22-27). In multivariable analysis, participants in the PrEP period had decreased odds of CAI (adjusted OR: 0.49, 95% CI 0.28, 0.84). PrEP use was not associated with risk compensation.

Indexed as

Pre-Exposure ProphylaxisSexual and Gender MinoritiesSexual BehaviorAdultChlamydia InfectionsFemaleGonorrheaHumansMaleNigeriaSexually Transmitted DiseasesYoung AdultPre-exposure prophylaxisRisk adjustment behaviorsSexual and gender minoritySexually transmitted infectionsSexual orientation

Identifiers

PMID38684621
PMCPMC11758484

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.