Evidence map›Paper›PMID 38684565›Full record

ArticleInternational journal of behavioral medicine2025

Loneliness, Methamphetamine Use, and Cardiovascular Risk Factors Among Sexual Minority Men in the COVID-19 Era.

Emily J Ross, Daniel E Jimenez, Delaram Ghanooni, Armando Mendez, Sabina Hirshfield, Keith J Horvath, Britt DeVries, Samantha E Dilworth, Adam W Carrico, Claudia A Martinez

Abstract read
In one paragraph

Article in International journal of behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily J RossDepartment of Public Health Sciences, University of Miami, 1120 NW 14th Street, Miami, FL, 33136, USA.ORCID http://orcid.org/0000-0002-6003-7855
Daniel E JimenezDepartment of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1436, Miami, FL, 33136, USA.ORCID http://orcid.org/0000-0003-2135-0619
Delaram GhanooniDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Miami, FL, 33136, USA.ORCID http://orcid.org/0000-0003-2340-9573
Armando MendezDivision of Endocrinology, Diabetes and Metabolism and the Diabetes Research Institute, Department of Medicine, University of Miami Miller School of Medicine, 1450 NW 10 Ave, Miami, FL, 33136, USA.ORCID http://orcid.org/0000-0003-1859-0822
Sabina HirshfieldDepartment of Medicine, STAR Program, SUNY Downstate Health Sciences University, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA.ORCID http://orcid.org/0000-0002-2649-469X
Keith J HorvathDepartment of Psychology, San Diego State University, Alvarado Court, San Diego, 6363, CA, USA.ORCID http://orcid.org/0000-0001-7569-2839
Britt DeVriesDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Miami, FL, 33136, USA.
Samantha E DilworthDepartment of Medicine, Center for AIDS Prevention Studies, University of California San Francisco, 550 16 Street, San Francisco, CA, 94158, USA.ORCID http://orcid.org/0000-0002-5451-5486
Adam W CarricoDepartment of Public Health Sciences, Miller School of Medicine, University of Miami, 1120 NW 14th Street, Miami, FL, 33136, USA.ORCID http://orcid.org/0000-0002-8146-5701
Claudia A MartinezCardiovascular Division, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th Street, Miami, FL, 33136, USA. cmartinez5@med.miami.edu.ORCID http://orcid.org/0000-0002-2489-6193

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Rana Chakraborty · 2007 to 2026
$33.8M
Supporting Treatment Adherence For Resilience and Thriving (START): A MHealth Intervention to Improve ART Adherence For HIV-Positive Stimulant Using Men - Diversity SupplementR01DA049843 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRICO, ADAM WAYNE · 2019 to 2023
$3.9M
Developing a U.S. National Cohort to Improve Virologic Suppression among Stimulant-using Men Living with HIV.UH3DA058304 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Adam Wayne Carrico, Monica Gandhi · 2025 to 2026
$3.6M
Health Promotion in the Prevention of Anxiety and Depression: The Happy Older Latinos are Active (HOLA Study)R01MD012610 · NIMHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI JIMENEZ, DANIEL ENRIQUE · 2019 to 2023
$3.5M
Relationship between methamphetamine use, viral reservoir dynamics and clinical progression in treated HIV infectionR01DA058437 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Adam Wayne Carrico, Mario Stevenson · 2023 to 2026
$2.6M
Syndemics, the microbiome, and mucosal inflammation involved in HIV acquisitionF32AI162229 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CHERENACK, EMILY MELLISSA · 2021 to 2023
$211k
NIAID NIH HHS F32 AI162229NIAID NIH HHS P30 AI073961NIDA NIH HHS R01 DA049843NIDA NIH HHS R01 DA058437NIDA NIH HHS UH3 DA058304NIH HHS 1F32AI162229NIH HHS P30AI073961NIH HHS R01-DA049843-01S1NIMHD NIH HHS R01 MD012610
6 · The paper itself

Abstract

backgroundImportant gaps exist in our understanding of loneliness and biobehavioral outcomes among sexual minority men (SMM), such as faster HIV disease progression. At the same time, SMM who use methamphetamine are approximately one-third more likely than non-users to develop cardiovascular disease. This study examined associations of loneliness, stimulant use, and cardiovascular risk in SMM with and without HIV.

methodParticipants were enrolled from August 2020 to February 2022 in a 6-month prospective cohort study. The study leveraged self-report baseline data from 103 SMM, with a subset of 56 SMM that provided a blood sample to measure markers of cardiovascular risk.

resultsLoneliness showed negative bivariate associations with total cholesterol and LDL cholesterol in the cardiometabolic subsample (n = 56). SMM with methamphetamine use (t(101) = 2.03, p < .05; d = .42) and those that screened positive for a stimulant use disorder (t(101) = 2.07, p < .05; d = .46) had significantly higher mean loneliness scores. In linear regression analyses, negative associations of loneliness with LDL and total cholesterol were observed only among SMM who used methamphetamine.

conclusionWe observed lower cholesterol in SMM reporting loneliness and methamphetamine use. Thus, in addition to the observed associations of loneliness with cholesterol, there are important medical consequences of methamphetamine use including cardiovascular risk, higher HIV acquisition risk and progression, as well as stimulant overdose death. This cross-sectional study underscores the need for clinical research to develop and test interventions targeting loneliness among SMM with stimulant use disorders.

Indexed as

Amphetamine-Related DisordersCardiovascular DiseasesCOVID-19Heart Disease Risk FactorsLonelinessMethamphetamineSexual and Gender MinoritiesAdultCholesterolHIV InfectionsHumansMaleMiddle AgedProspective StudiesRisk FactorsCholesterolMethamphetamineHIVLonelinessSexual minority healthSocial isolationStimulant use

Identifiers

PMID38684565
PMCPMC11518875

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.