Evidence map›Paper›PMID 38684317›Full record

ArticleRNA (New York, N.Y.)2024

The modification landscape of

Mariana D Mandler, Siddhardha S Maligireddy, Wilfried M Guiblet, Christina M Fitzsimmons, Kayla S McDonald, Delayna L Warrell, Pedro J Batista

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Combined Prokaryotic Transcriptomics and Proteomics Analysis of ClinicalInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mariana D MandlerLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0003-1609-6871
Siddhardha S MaligireddyLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0003-1143-7788
Wilfried M GuibletLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0001-6319-3418
Christina M FitzsimmonsLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0002-6743-2671
Kayla S McDonaldLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Delayna L WarrellLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Pedro J BatistaLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA pedro.batista@nih.gov.ORCID 0000-0003-1055-2354

Funding

Regulation of RNA biogenesis and function by RNA modificationsZIABC011766 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DE OLIVEIRA RODRIGUES BATISTA, PEDRO · 2017 to 2025
$10.6M
6 · The paper itself

Abstract

RNA modifications have a substantial impact on tRNA function, with modifications in the anticodon loop contributing to translational fidelity and modifications in the tRNA core impacting structural stability. In bacteria, tRNA modifications are crucial for responding to stress and regulating the expression of virulence factors. Although tRNA modifications are well-characterized in a few model organisms, our knowledge of tRNA modifications in human pathogens, such as

Indexed as

Escherichia coliPseudomonas aeruginosaRNA, TransferAnticodonNucleic Acid ConformationRNA, BacterialRNA Processing, Post-TranscriptionalAnticodonRNA, BacterialRNA, Transfer4-thiouridineacp3UP. aeruginosatRNAtRNA modificationvariable region

Identifiers

PMID38684317
PMCPMC11251520

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.