Evidence map›Paper›PMID 38684316›Full record

ArticleRNA (New York, N.Y.)2024

Human T-cell leukemia virus type 1 uses a specific tRNA

Yu-Ci Syu, Joshua Hatterschide, Christina R Budding, Yingke Tang, Karin Musier-Forsyth

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The Roles of tRNA-Derived Fragments in Cancer: Updates and Perspectives.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Ci SyuDepartment of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, Ohio 43210, USA.
Joshua HatterschideDepartment of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, Ohio 43210, USA.
Christina R BuddingDepartment of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, Ohio 43210, USA.
Yingke TangDepartment of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, Ohio 43210, USA.
Karin Musier-ForsythDepartment of Chemistry and Biochemistry, Center for RNA Biology, and Center for Retrovirus Research, The Ohio State University, Columbus, Ohio 43210, USA musier-forsyth.1@osu.edu.

Funding

Structural Biology CoreU54AI170855 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI Bruce Edward Torbett · 2022 to 2026
$36.7M
Cellular, molecular, and biochemical sciences training grantT32GM141955 · NIGMS · OHIO STATE UNIVERSITY · PI Jane Elizabeth Jackman, JESSE J KWIEK · 2021 to 2026
$2.2M
Cellular Factors Critical for Initiation of HIV-1 Reverse TranscriptaseR01AI150493 · NIAID · OHIO STATE UNIVERSITY · PI MUSIER-FORSYTH, KARIN M · 2020 to 2022
$1.2M
NIAID NIH HHS R01 AI150493NIAID NIH HHS U54 AI170855NIGMS NIH HHS T32 GM141955
6 · The paper itself

Abstract

Human T-cell leukemia virus type 1 (HTLV-1) is the only oncogenic human retrovirus discovered to date. All retroviruses are believed to use a host cell tRNA to prime reverse transcription (RT). In HTLV-1, the primer-binding site (PBS) in the genomic RNA is complementary to the 3' 18 nucleotides (nt) of human tRNA

Indexed as

Human T-lymphotropic virus 1Reverse TranscriptionRNA, Transfer, ProHumansRNA, ViralRNA, Transfer, ProRNA, ViralHTLV-1isodecoderm1A58reverse transcriptiontRNA primer

Identifiers

PMID38684316
PMCPMC11251516

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.