Evidence map›Paper›PMID 38684115›Full record

ReviewAnnual review of virology2024

Controlling Much? Viral Control of Host Chromatin Dynamics.

Laurel E Kelnhofer-Millevolte, Edward A Arnold, Daniel H Nguyen, Daphne C Avgousti

Abstract readReview
In one paragraph

Review in Annual review of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurel E Kelnhofer-MillevolteMedical Scientist Training Program, University of Washington, Seattle, Washington, USA.
Edward A ArnoldDepartment of Microbiology, University of Washington, Seattle, Washington, USA.
Daniel H NguyenHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA; email: avgousti@fredhutch.org.
Daphne C AvgoustiHuman Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA; email: avgousti@fredhutch.org.

Funding

Investigating chromatin mechanisms using viral systemsR35GM133441 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daphne Christina Avgousti · 2019 to 2026
$3.8M
Viral Pathogenesis Training ProgramT32AI083203 · NIAID · UNIVERSITY OF WASHINGTON · PI BLOOM, JESSE D, LAGUNOFF, MICHAEL · 2009 to 2023
$2.7M
NIAID NIH HHS T32 AI083203NIGMS NIH HHS R35 GM133441
6 · The paper itself

Abstract

Viruses are exemplary molecular biologists and have been integral to scientific discovery for generations. It is therefore no surprise that nuclear replicating viruses have evolved to systematically take over host cell function through astoundingly specific nuclear and chromatin hijacking. In this review, we focus on nuclear replicating DNA viruses-herpesviruses and adenoviruses-as key examples of viral invasion in the nucleus. We concentrate on critical features of nuclear architecture, such as chromatin and the nucleolus, to illustrate the complexity of the virus-host battle for resources in the nucleus. We conclude with a discussion of the technological advances that have enabled the discoveries we describe and upcoming steps in this burgeoning field.

Indexed as

ChromatinHost-Pathogen InteractionsAdenoviridaeAnimalsCell NucleusHerpesviridaeHumansVirus ReplicationChromatinadenoviruschromatinherpesvirushistoneslatencynucleus

Identifiers

PMID38684115
PMCPMC13244615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.