Evidence map›Paper›PMID 38683989›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Proteolytic stability and aggregation in a key metabolic enzyme of bacteria.

Dan Pollack, Takashi Nozoe, Edo Kussell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dan PollackDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10003.ORCID 0000-0003-4955-1826
Takashi NozoeDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo 153-8902, Japan.ORCID 0000-0003-2556-6484
Edo KussellDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, NY 10003.

Funding

Memory in Bacterial Responses to Fluctuating StressR01GM120231 · NIGMS · NEW YORK UNIVERSITY · PI KUSSELL, EDO L · 2016 to 2019
$1.3M
Gene Regulation and Memory in Bacterial Metabolism and Antibiotic ResistanceR01GM148703 · NIGMS · NEW YORK UNIVERSITY · PI EDO L KUSSELL · 2023 to 2026
$1.3M
NIGMS NIH HHS R01 GM120231NIGMS NIH HHS R01 GM148703
6 · The paper itself

Abstract

Proteins that are kinetically stable are thought to be less prone to both aggregation and proteolysis. We demonstrate that the classical

Indexed as

beta-GalactosidaseEscherichia coliLac OperonProteolysisEnzyme StabilityEscherichia coli ProteinsProtein Aggregatesbeta-GalactosidaseEscherichia coli ProteinsProtein Aggregateslac operonprotein aggregationprotein degradationssrAβ-galactosidase

Identifiers

PMID38683989
PMCPMC11087809

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.