Evidence map›Paper›PMID 38683985›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

The tRNA

Kamlesh Pawar, Takuya Kawamura, Yohei Kirino

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Dissecting the small RNA code of inflammatory bowel disease.Molecular medicine (Cambridge, Mass.) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kamlesh Pawar *Computational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107.ORCID 0000-0002-9767-0152
Takuya Kawamura *Computational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107.ORCID 0000-0002-0355-5699
Yohei KirinoComputational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107.ORCID 0000-0001-5232-4742

Funding

piRNA biogenesis ruled by PIWI-TUDOR interactionR01GM106047 · NIGMS · THOMAS JEFFERSON UNIVERSITY · PI KIRINO, YOHEI · 2013 to 2022
$2.8M
tRNA-derived non-coding RNAs in ASM function and in asthmaR01HL150560 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI DESHPANDE, DEEPAK A, KIRINO, YOHEI · 2020 to 2023
$2.4M
Role of Toll-like receptor-induced short non-coding RNAs in innate immune responseR21AI151641 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI KIRINO, YOHEI · 2021 to 2022
$429k
Role of rRNA-derived short non-coding RNAs in innate immune responseR21AI168975 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI KIRINO, YOHEI · 2022 to 2023
$429k
Endogenous single-stranded RNA ligands for endosomal Toll-like receptorsR21AI171366 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI KIRINO, YOHEI · 2023 to 2024
$429k
NHLBI NIH HHS R01 HL150560NIAID NIH HHS R21 AI151641NIAID NIH HHS R21 AI168975NIAID NIH HHS R21 AI171366NIGMS NIH HHS R01 GM106047
6 · The paper itself

Abstract

Toll-like receptors (TLRs) are crucial components of the innate immune system. Endosomal TLR7 recognizes single-stranded RNAs, yet its endogenous ssRNA ligands are not fully understood. We previously showed that extracellular (ex-) 5'-half molecules of tRNA

Indexed as

MacrophagesToll-Like Receptor 7HumansLigandsLipopolysaccharidesMycobacterium tuberculosisRNA, Transfer, HisLigandsLipopolysaccharidesRNA, Transfer, HisTLR7 protein, humanToll-Like Receptor 7macrophageshort non-coding RNATLR7tRNA halfValine

Identifiers

PMID38683985
PMCPMC11087793

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.