Evidence map›Paper›PMID 38683976›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Frequent nonhomologous replacement of replicative helicase loaders by viruses in

Kento Tominaga, Shogo Ozaki, Shohei Sato, Tsutomu Katayama, Yuki Nishimura, Kimiho Omae, Wataru Iwasaki

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kento TominagaDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-0882, Japan.
Shogo OzakiDepartment of Molecular Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.ORCID 0000-0002-4384-1366
Shohei SatoDepartment of Molecular Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Tsutomu KatayamaDepartment of Molecular Biology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan.ORCID 0000-0001-9994-1684
Yuki NishimuraDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-0882, Japan.
Kimiho OmaeDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-0882, Japan.
Wataru IwasakiDepartment of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-0882, Japan.ORCID 0000-0002-9169-9245

Funding

MEXT JPMXD1521474594MEXT | Japan Society for the Promotion of Science (JSPS) 19H05688MEXT | Japan Society for the Promotion of Science (JSPS) 22H00557MEXT | Japan Society for the Promotion of Science (JSPS) 22H04925MEXT | Japan Society for the Promotion of Science (JSPS) 23K05640MEXT | JST | Core Research for Evolutional Science and Technology (CREST) JPMJCR19S2
6 · The paper itself

Abstract

Several microbial genomes lack textbook-defined essential genes. If an essential gene is absent from a genome, then an evolutionarily independent gene of unknown function complements its function. Here, we identified frequent nonhomologous replacement of an essential component of DNA replication initiation, a replicative helicase loader gene, in

Indexed as

DNA HelicasesDNA ReplicationPhylogenyVibrionaceaeBacterial ProteinsBacteriophagesDnaB HelicasesEvolution, MolecularGenome, BacterialVibrioViral ProteinsBacterial ProteinsDnaB HelicasesDNA HelicasesViral ProteinsbioinformaticsDNA helicase loaderfunction-unknown genegenome evolutionvirus

Identifiers

PMID38683976
PMCPMC11087808

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.