Evidence map›Paper›PMID 38683745›Full record

ArticleEnvironmental health perspectives2024

A Hazard-Based Framework for Identifying Safer Alternatives to Classes of Chemicals: A Case Study on Phthalates in Consumer Products.

Marissa N Smith, Sascha Stump, Saskia K van Bergen, Holly G Davies, Elinor Fanning, Rae Eaton, Craig C Manahan, Amber Sergent, Ken Zarker

Abstract read
In one paragraph

Article in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. HazChemNet: A Deep Learning Model for Hazardous Chemical Prediction.International journal of molecular sciences · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marissa N SmithHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.ORCID 0009-0004-0950-3824
Sascha StumpHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.
Saskia K van BergenHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.
Holly G DaviesEnvironmental Public Health Sciences, Washington State Department of Health, Tumwater, Washington, USA.
Elinor FanningEnvironmental Public Health Sciences, Washington State Department of Health, Tumwater, Washington, USA.
Rae EatonHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.
Craig C ManahanHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.
Amber SergentHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.
Ken ZarkerHazardous Waste & Toxics Reduction, Washington State Department of Ecology, Lacey, Washington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHumans are exposed to hazardous chemicals found in consumer products. In 2019, the Pollution Prevention for Healthy People and Puget Sound Act was passed in Washington State. This law is meant to reduce hazardous chemicals in consumer products and protect human health and the environment. The law directs the Washington State Department of Ecology to assess chemicals and chemical classes found in products, determine whether there are safer alternatives, and make regulatory determinations.

objectivesTo implement the law, the Department of Ecology developed a hazard-based framework for identifying safer alternatives to classes of chemicals.

methodsWe developed a hazard-based framework, termed the "Criteria for Safer," to set a transparent bar for determining whether new chemical alternatives are safer than existing classes of chemicals. Our "Criteria for Safer" is a framework that builds on existing hazard assessment methodologies and published approaches for assessing chemicals and chemical classes. DISCUSSION: We describe implementation of our criteria using a case study on the phthalates chemical class in two categories of consumer products: vinyl flooring and fragrances used in personal care and beauty products. Additional context and considerations that guided our decision-making process are also discussed, as well as benefits and limitations of our approach. This paper gives insight into our development and implementation of a hazard-based framework to address classes of chemicals in consumer products and will aid others working to build and employ similar approaches. https://doi.org/10.1289/EHP13549.

Indexed as

Hazardous SubstancesPhthalic AcidsConsumer Product SafetyCosmeticsEnvironmental ExposureEnvironmental PollutantsHumansRisk AssessmentWashingtonCosmeticsEnvironmental PollutantsHazardous SubstancesPhthalic Acids

Identifiers

PMID38683745
PMCPMC11057665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.