ArticleApplied biochemistry and biotechnology2024
Onco-therapeutic Effect of Novel Triterpenoid Compound Oleanolic Acid Isolated and Characterized from the Methanolic Extract of Coldenia procumbens (Linn.).
Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
India is considered a hub for a wide range of phytochemicals due to its rich biodiversity, which indeed flourished with many folk medicines and treatments. Phytochemicals are secondary metabolites synthesized in plants to protect themselves from deteriorating environmental stress and defense against pathogens. In the present study, we aimed to explore the strong anticancer potential of the bioactive compound present in the leaf extract of Coldenia procumbens (L.). The bioactive compound oleanolic acid was first time reported in the plant and was successfully isolated, characterized with various spectroscopic analyses. The in vitro study results explored that oleanolic acid has shown a potent cytotoxic effect against human hepatocellular carcinoma cell lines with a low IC
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