ArticleEuropean journal of applied physiology2024
The effect of chronotropic incompetence on physiologic responses during progressive exercise in people with Parkinson's disease.
Article in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Effects of inspiratory muscle training on oxygen consumption, muscle oxygen, and physical activity levels in patients with Parkinson's disease.Scientific reports · 2025Trial
- Physical Activity and Exercise for People with Parkinson's Disease: The Past, Present, and Future.Movement disorders : official journal of the Movement Disorder Society · 2026Review
- Advice to people with Parkinson's in my clinic: Get a cardiopulmonary exercise test.Journal of Parkinson's disease · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHeart rate (HR) response is likely to vary in people with Parkinson's disease (PD), particularly for those with chronotropic incompetence (CI). This study explores the impact of CI on HR and metabolic responses during cardiopulmonary exercise test (CPET) in people with PD, and its implications for exercise intensity prescription.
methodsTwenty-eight participants with mild PD and seventeen healthy controls underwent CPET to identify the presence or absence of CI. HR and metabolic responses were measured at submaximal (first (VT1) and second (VT2) ventilatory thresholds), and at peak exercise. Main outcome measures were HR, oxygen consumption (VO
resultsCI was present in 13 (46%) PD participants (PDCI), who during CPET, exhibited blunted HR responses compared to controls and PD non-CI beyond 60% of maximal workload (p ≤ 0.05). PDCI presented a significantly lower HR at VT2, and peak exercise compared to PD non-CI and controls (p ≤ 0.001). VO
conclusionAlthough poorly understood, the presence of CI in PD and its effect on HR and metabolic responses during incremental exercise is significant and important to consider when programming aerobic exercises.
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