Evidence map›Paper›PMID 38683272›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study.

Abdulaziz H Alhazmi, Khalid M Alameer, Bandar M Abuageelah, Amal Yahya Gharawi, Ehab Farouq Hakami, Taif Ali Zogel, Abdullah Jaber Almalki, Ebhar Gubran Magrashi, Wafa Ali Alharbi, Ramis Mohammed Manni and 4 more

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Rising Prevalence of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abdulaziz H AlhazmiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia. abalhazmi@jazanu.edu.sa.
Khalid M AlameerFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Bandar M AbuageelahDepartment of Medicine and Surgery, Batterjee Medical College, Aseer, 62451, Saudi Arabia.
Amal Yahya GharawiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Ehab Farouq HakamiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Taif Ali ZogelFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Abdullah Jaber AlmalkiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Ebhar Gubran MagrashiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Wafa Ali AlharbiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Ramis Mohammed ManniFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Atheer Ali BuaytiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Ahmad A AlharbiFaculty of Medicine, Jazan University, Jazan, 45142, Saudi Arabia.
Nabil S DhayhiKing Fahad Central Hospital, Ministry of Health, Jazan, 45142, Saudi Arabia.
Moayad HaddadKing Fahad Central Hospital, Ministry of Health, Jazan, 45142, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBacterial meningitis poses significant medical challenges due to its acute inflammatory nature and potential for severe neurological complications, emphasizing the need for prompt diagnosis and treatment. Limited data exists on its epidemiology and antimicrobial resistance trends among hospitalized patients in Saudi Arabia. This study aimed to investigate these factors at a tertiary care hospital over six years.

methodsA retrospective analysis was conducted on cerebrospinal fluid samples results from 222 bacterial meningitis cases among hospitalized patients between 2018 and 2023. Demographic, clinical, microbiological data, and antibiotic susceptibility patterns were collected and analyzed.

resultsPseudomonas aeruginosa (43%) was the predominant pathogen isolated. Neonates (16%) and children (47%) were most affected population. Nosocomial meningitis accounted for 92% of cases, mainly in the intensive care settings (50.45%). Extended-spectrum beta-lactamase was the leading resistance pattern (12.2%). Seasonal variation was observed, with a peak incidence in October-November.

conclusionThe study highlights the substantial burden of bacterial meningitis among hospitalized patients, especially among high-risk groups. Emerging antimicrobial resistance emphasizes the need for optimized surveillance and stewardship. Future prospective research employing molecular techniques across multiple centers in the country is warranted to enhance understanding and guide public health strategies in Saudi Arabia.

Indexed as

Anti-Bacterial AgentsCross InfectionMeningitis, BacterialTertiary Care CentersAdolescentAdultAgedBacteriaChildChild, PreschoolDrug Resistance, BacterialFemaleHospitalizationHumansIncidenceInfantAnti-Bacterial AgentsAntimicrobial resistanceBacterial meningitisGram-negativeNosocomial infectionsSaudi Arabia

Identifiers

PMID38683272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.