Evidence map›Paper›PMID 38683167›Full record

ReviewFuture microbiology2024

Nanomaterial-based drug-delivery system as an aid to antimicrobial photodynamic therapy in treating oral biofilm.

Guanwen Sun, Shan Huang, Shaofeng Wang, Yijun Li

Abstract readReview
In one paragraph

Review in Future microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guanwen SunDepartment of stomatology, Fujian Medical University Xiamen Humanity Hospital, Xiamen, China.
Shan HuangDepartment of stomatology, Zhongshan Hospital affiliated to Xiamen University, Xiamen, China.
Shaofeng WangDepartment of Endodontics, Stomatological Hospital of Xiamen Medical College, Xiamen, China.
Yijun LiDepartment of Endodontics, Stomatological Hospital of Xiamen Medical College, Xiamen, China.ORCID 0000-0003-0602-5041

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diverse microorganisms live as biofilm in the mouth accounts for oral diseases and treatment failure. For decades, the prevention and treatment of oral biofilm is a global challenge. Antimicrobial photodynamic therapy (aPDT) holds promise for oral biofilm elimination due to its several traits, including broad-spectrum antimicrobial capacity, lower possibility of resistance and low cytotoxicity. However, the physicochemical properties of photosensitizers and the biological barrier of oral biofilm have limited the efficiency of aPDT. Nanomaterials has been used to fabricate nanocarriers to improve photosensitizer properties and thus enhance antimicrobial effect. In this review, we have discussed the challenges of aPDT used in dentistry, categorized the nanomaterial-delivery system and listed the possible mechanisms involved in nanomaterials when enhancing aPDT effect.

Indexed as

BiofilmsDrug Delivery SystemsNanostructuresPhotochemotherapyPhotosensitizing AgentsAnimalsAnti-Bacterial AgentsAnti-Infective AgentsBacteriaDrug CarriersHumansMouthAnti-Bacterial AgentsAnti-Infective AgentsDrug CarriersPhotosensitizing Agentsantimicrobial photodynamic therapymechanismnanomaterialoral biofilmphotosensitizer

Identifiers

PMID38683167
PMCPMC11259068

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.