Evidence map›Paper›PMID 38682808›Full record

ArticleEuropean journal of neurology2024

Potential effects of a mobile stroke unit on time to treatment and outcome in patients treated with thrombectomy or thrombolysis: A Danish-German cross-border analysis.

Susanna Bluhm, Peter Schramm, Yannic Spreen-Ledebur, Sebastian Bluhm, Thomas F Münte, Morten Rye Eiersted, Frauke Wolfram, Robbert-Jan Roderick van Hooff, Troels Wienecke, Georg Royl

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Article in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Susanna BluhmDepartment of Neurology, University of Lübeck, Lübeck, Germany.
Peter SchrammDepartment of Neuroradiology, University of Lübeck, Lübeck, Germany.
Yannic Spreen-LedeburPlan D GmbH, Berlin, Germany.
Sebastian BluhmPlan D GmbH, Berlin, Germany.
Thomas F MünteDepartment of Neurology, University of Lübeck, Lübeck, Germany.
Morten Rye EierstedZealand University Hospital, Roskilde, Denmark.
Frauke WolframDepartment of Radiology, Zealand University Hospital, Roskilde, Denmark.
Robbert-Jan Roderick van HooffDepartment of Neurology, Zealand University Hospital, Roskilde, Denmark.ORCID 0000-0003-2712-2772
Troels WieneckeDepartment of Neurology, Zealand University Hospital, Roskilde, Denmark.
Georg RoylDepartment of Neurology, University of Lübeck, Lübeck, Germany.

Funding

European Union
6 · The paper itself

Abstract

background and purposeA mobile stroke unit (MSU) reduces delays in stroke treatment by allowing thrombolysis on board and avoiding secondary transports. Due to the beneficial effect in comparison to conventional emergency medical services, current guidelines recommend regional evaluation of MSU implementation.

methodsIn a descriptive study, current pathways of patients requiring a secondary transport for mechanical thrombectomy were reconstructed from individual patient records within a Danish (n = 122) and an adjacent German region (n = 80). Relevant timestamps included arrival times (on site, primary hospital, thrombectomy centre) as well as the initiation of acute therapy. An optimal MSU location for each region was determined. The resulting time saving was translated into averted disability-adjusted life years (DALYs).

resultsFor each region, the optimal MSU location required a median driving time of 35 min to a stroke patient. Time savings in the German region (median [Q1; Q3]) were 7 min (-15; 31) for thrombolysis and 35 min (15; 61) for thrombectomy. In the Danish region, the corresponding time savings were 20 min (8; 30) and 43 min (25; 66). Assuming 28 thrombectomy cases and 52 thrombolysis cases this would translate to 9.4 averted DALYs per year justifying an annual net MSU budget of $0.8M purchasing power parity dollars (PPP-$) in the German region. In the Danish region, the MSU would avert 17.7 DALYs, justifying an annual net budget of PPP-$1.7M.

conclusionThe effects of an MSU can be calculated from individual patient pathways and reflect differences in the hospital infrastructure between Denmark and Germany.

Indexed as

Mobile Health UnitsStrokeThrombectomyThrombolytic TherapyTime-to-TreatmentAgedAged, 80 and overDenmarkFemaleGermanyHumansMaleMiddle AgedTreatment Outcomedrip and ship modelmobile stroke unitstrokethrombectomythrombolysis

Identifiers

PMID38682808
PMCPMC11295161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.