Evidence map›Paper›PMID 38682597›Full record

ArticleJournal of toxicology and environmental health. Part A2024

Exposure to emissions generated by 3-dimensional printing with polycarbonate: effects on peripheral vascular function, cardiac vascular morphology and expression of markers of oxidative stress in male rat cardiac tissue.

Kristine Krajnak, Mariana Farcas, Diana Richardson, Mary Anne Hammer, Stacey Waugh, Walter McKinney, Alycia Knepp, Mark Jackson, Dru Burns, Ryan LeBouf and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kristine KrajnakHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Mariana FarcasHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Diana RichardsonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Mary Anne HammerHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Stacey WaughHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Walter McKinneyHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Alycia KneppHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Mark JacksonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Dru BurnsRespiratory Health Division, Morgantown, WV, USA.
Ryan LeBoufRespiratory Health Division, Morgantown, WV, USA.
Joanna MathesonConsumer Product Safety Commission, Rockville, MD, USA.
Treye ThomasConsumer Product Safety Commission, Rockville, MD, USA.
Yong QianHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Three-dimensional (3D) printing with polycarbonate (PC) plastic occurs in manufacturing settings, homes, and schools. Emissions generated during printing with PC stock and bisphenol-A (BPA), an endocrine disrupter in PC, may induce adverse health effects. Inhalation of 3D printer emissions, and changes in endocrine function may lead to cardiovascular dysfunction. The goal of this study was to determine whether there were any changes in markers of peripheral or cardiovascular dysfunction in animals exposed to PC-emissions. Male Sprague Dawley rats were exposed to PC-emissions generated by 3D printing for 1, 4, 8, 15 or 30 d. Exposure induced a reduction in the expression of the antioxidant catalase (

Indexed as

Oxidative StressPolycarboxylate CementPrinting, Three-DimensionalRats, Sprague-DawleyAir PollutantsAnimalsBenzhydryl CompoundsBiomarkersBisphenol A CompoundsHeartMaleMyocardiumNitric Oxide Synthase Type IIIPhenolsRatsAir PollutantsBenzhydryl CompoundsBiomarkersbisphenol ABisphenol A CompoundsNitric Oxide Synthase Type IIIPhenolspolycarbonatePolycarboxylate Cementcardiovascular functioncardiovascular morphologyInhalationparticulate matterpolycarbonate emissionsthree-dimensional (3D) printing

Identifiers

PMID38682597
PMCPMC11625379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.