Evidence map›Paper›PMID 38682293›Full record

ArticleNanoscale2024

Single-molecule imaging of aquaporin-4 array dynamics in astrocytes.

Anna-Lena Zepernick, Vanya Metodieva, Noelia Pelegrina-Hidalgo, Anna H Lippert, Mathew H Horrocks, Juan A Varela

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Advanced optical microscopy methods forBiophysical reviews · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna-Lena ZepernickSchool of Biology, University of St Andrews, St Andrews, UK.
Vanya MetodievaSchool of Biology, University of St Andrews, St Andrews, UK.
Noelia Pelegrina-HidalgoEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh, UK.
Anna H LippertInstitute for System Immunology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
Mathew H HorrocksEaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0001-5495-5492
Juan A VarelaSchool of Physics and Astronomy, University of St Andrews, St Andrews, UK. jv32@st-andrews.ac.uk.ORCID http://orcid.org/0000-0003-1901-1378

Funding

Wellcome Trust
6 · The paper itself

Abstract

Aquaporin-4 (AQP4) facilitates water transport across astrocytic membranes in the brain, forming highly structured nanometric arrays. AQP4 has a central role in regulating cerebrospinal fluid (CSF) circulation and facilitating the clearance of solutes from the extracellular space of the brain. Adrenergic signaling has been shown to modulate the volume of the extracellular space of the brain

Indexed as

Aquaporin 4AstrocytesIsoproterenolSingle Molecule ImagingAdrenergic beta-AgonistsAnimalsBrainCells, CulturedMiceReceptors, Adrenergic, betaWaterAdrenergic beta-AgonistsAquaporin 4IsoproterenolReceptors, Adrenergic, betaWater

Identifiers

PMID38682293
PMCPMC11097139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.