Evidence map›Paper›PMID 38682242›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2024

Phenylephrine alters phase synchronization between cerebral blood velocity and blood pressure in ME/CFS with orthostatic intolerance.

Marvin S Medow, Julian M Stewart

Abstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marvin S MedowDepartment of Pediatrics, New York Medical College, Valhalla, New York, United States.ORCID 0000-0001-6535-7316
Julian M StewartDepartment of Pediatrics, New York Medical College, Valhalla, New York, United States.

Funding

Local Vasoconstriction in Postural Tachycardia SyndromeR01HL074873 · NHLBI · NEW YORK MEDICAL COLLEGE · PI STEWART, JULIAN M · 2004 to 2013
$3.4M
Cardiovagal baroreflex deficits impair neurovascular coupling and cognition in Postural Tachycardia SyndromeR01HL134674 · NHLBI · NEW YORK MEDICAL COLLEGE · PI STEWART, JULIAN M · 2017 to 2020
$2.5M
Mechanisms of Vasovagal SyncopeR01HL112736 · NHLBI · NEW YORK MEDICAL COLLEGE · PI STEWART, JULIAN M · 2013 to 2016
$2.1M
Mechanism of Chemoreflex and Baroreflex alterations causing Postural Tachycardia Syndrome in POTS patients with orthostatic hyperpnea and hypocapnia.R56HL162752 · NHLBI · NEW YORK MEDICAL COLLEGE · PI MEDOW, MARVIN S, STEWART, JULIAN M · 2022 to 2022
$709k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 1R56HL162752HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) RO1 HL 074873HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) RO1 HL 112736NHLBI NIH HHS R01 HL074873NHLBI NIH HHS R01 HL112736NHLBI NIH HHS R01 HL134674NHLBI NIH HHS R56 HL162752Solve ME/CFS Initiative (SMCI)
6 · The paper itself

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) with orthostatic intolerance (OI) is characterized by neurocognitive deficits perhaps related to upright hypocapnia and loss of cerebral autoregulation (CA). We performed N-back neurocognition testing and calculated the phase synchronization index (PhSI) between arterial pressure (AP) and cerebral blood velocity (CB

Indexed as

Blood PressureCerebrovascular CirculationOrthostatic IntolerancePhenylephrineAdultArterial PressureBlood Flow VelocityCase-Control StudiesCognitionFatigue Syndrome, ChronicFemaleHeart RateHomeostasisHumansMalePostural Orthostatic Tachycardia SyndromePhenylephrinemyalgic encephalomyelitis/chronic fatigue syndromeN-back testingphase synchronizationphenylephrine

Identifiers

PMID38682242
PMCPMC11381003

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.