Evidence map›Paper›PMID 38681967›Full record

ArticleTherapeutic advances in infectious disease

Four-year variation in pathogen distribution and antimicrobial susceptibility of urosepsis: a single-center retrospective analysis.

Yu-Yun Wu, Pei Li, Zi-Ye Huang, Jian-He Liu, Bo-Wei Yang, Wen-Bo Zhou, Fei Duan, Guang Wang, Jiong-Ming Li

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu-Yun WuThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Pei LiThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Zi-Ye HuangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Jian-He LiuThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Bo-Wei YangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Wen-Bo ZhouThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Fei DuanThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China.
Guang WangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 374 Dian-Mian Avenue, Kunming, Yunnan, 650101, P. R. China.
Jiong-Ming LiThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 374 Dian-Mian Avenue, Kunming, Yunnan, 650101, P. R. China.ORCID https://orcid.org/0000-0001-8680-3872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Urosepsis is a common disease in urology, which is characterized by high treatment costs and high mortality. In the treatment of sepsis, anti-infection therapy is the most important means. However, the effect of empirical anti-infection therapy is often not ideal. Therefore, it is necessary to continuously monitor the prevalence of bacterial isolates in the blood culture of patients with urinary sepsis and their sensitivity to antibacterial drugs. This is of great significance to improve the efficacy of empirical antibiotic therapy for urosepsis. Objective: To elucidate the landscape of prevailing bacterial profiles and their antimicrobial susceptibilities in urosepsis cases, and to furnish robust clinical evidence to underpin the timely initiation of empirical antibiotic treatment. Methods: Collect the basic information and blood culture results of patients with urosepsis hospitalized from 2017 to 2020. Retrospective analysis of bacterial species and antimicrobial susceptibility in urosepsis and changes over 4 years. Results: Gram-negative bacteria (178 isolates, 75.11%) constituted the main pathogens causing urosepsis, followed by Gram-positive bacteria (46 isolates, 19.41%) and fungus (13 isolates, 5.48%). The sensitivity of ertapenem, meropenem, amikacin, and imipenem to Gram-negative bacteria all exceeded 85%. The sensitivity rates of levofloxacin, gentamicin, and ciprofloxacin are decreasing every year ( Conclusion: Analysis of blood culture results of patients more accurately reflected the etiology of urosepsis, mainly

Indexed as

antimicrobial susceptibilityblood cultureclinical evidencepathogen distributionurosepsis

Identifiers

PMID38681967
PMCPMC11055490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.