Evidence map›Paper›PMID 38681946›Full record

ArticleAnnals of burns and fire disasters2023

Evaluation of the Impact of Exposure To Heat and to By-Products of Combustion on the Health of Firefighters.

A C Boggi, J B do Amaral, A L L Bacchi, V M Nascimento, R L Voegels, J M B Dos Santos, G Grimaldi, K Basseto de Oliveira Araújo, V Pavão, D A Passaretti and 3 more

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Annals of burns and fire disasters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

A C BoggiENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
J B do AmaralENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
A L L BacchiENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
V M NascimentoFire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
R L VoegelsDepartment of Ophthalmology and Otorhinolaryngology, University of São Paulo, São Paulo, Brazil.
J M B Dos SantosENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.
G GrimaldiHospital da Polícia Militar, Polícia Militar do Estado de São Paulo, São Paulo, Brazil.
K Basseto de Oliveira AraújoHospital da Polícia Militar, Polícia Militar do Estado de São Paulo, São Paulo, Brazil.
V PavãoFire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
D A PassarettiFire Department, Escola Superior de Bombeiros -- Polícia Militar do Estado de São Paulo, Franco da Rocha, Brazil.
A AldredPredikta Soluções em Pesquisa LTDA, São Paulo, Brazil.
G GomesPredikta Soluções em Pesquisa LTDA, São Paulo, Brazil.
R PezatoENT Research Lab, Department of Otorhinolaryngology and Head and Neck Surgery, Federal University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Firefighters are often exposed to high temperatures and by-products of combustion, which can affect their health. In this study, we assessed the impact of acute exposure of firefighters in fire simulators. Twenty male firefighters were exposed to fire simulators, and observed in four phases: pre-exposure (group 0, control) and after the end of the first (group 1), second (group 2), and fourth (group 3) weeks of training. Blood samples were collected and dosed to evaluate the response of the immune, inflammatory (C-reactive protein, IL6, and IL10), and endocrine systems (cortisone, total testosterone, free testosterone, SHBG, bioavailable testosterone, TSH, and free T4). In groups 0, 1, and 3, a thermographic evaluation was also carried out to study the temperature and body heat flow of the participants. Regarding the inflammatory process, an increase in C-reactive protein and a reduction in IL-10 were observed. With respect to hormonal markers, an increase in cortisol and reduced levels of free T4 and bioavailable testosterone were found after exposure, with recovery of testosterone levels in the final week of training. Thermoregulatory adaptation of the organism has been associated with changes in heat flow in the organism in people subjected to extreme temperatures, with emphasis on the performance of the lower limbs. Our findings demonstrate an inflammatory response with hormonal changes after exposure to fire and an adaptive response of thermal balance, which could aid understanding of the physiology of the human body in extreme situations.

Indexed as

firefighterfirefightingheathormonesinflammationthermoregulation

Identifiers

PMID38681946
PMCPMC11041887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.