Evidence map›Paper›PMID 38681794›Full record

ArticleJournal of intensive medicine2024

Severe asthma exacerbation: Changes in patient characteristics, management, and outcomes from 1997 to 2016 in 40 ICUs in the greater Paris area.

Romy Younan, Jean Loup Augy, Bertrand Hermann, Bertrand Guidet, Philippe Aegerter, Emmanuel Guerot, Ana Novara, Caroline Hauw-Berlemont, Amer Hamdan, Clotilde Bailleul and 4 more

Abstract read
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In one paragraph

Article in Journal of intensive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Romy YounanIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Jean Loup AugyIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Bertrand HermannIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Bertrand GuidetIntensive Care Unit, AP-HP, Saint Antoine Hospital, Universités de Sorbonne, Université Pierre et Marie Curie, Paris, France.
Philippe AegerterVersailles Saint-Quentin-en-Yvelines University, INSERM U1018, Groupe Interrégional de Recherche Clinique et d'Innovation, Île-de-France, France.
Emmanuel GuerotIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Ana NovaraIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Caroline Hauw-BerlemontIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Amer HamdanRespiratory Medicine Department, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Clotilde BailleulIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Francesca SantiIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Jean-Luc DiehlIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Nicolas PeronIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.
Nadia AissaouiIntensive Care Unit, AP-HP, Georges Pompidou European Hospital, Université de Paris, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite advances in asthma treatments, severe asthma exacerbation (SAE) remains a life-threatening condition in adults, and there is a lack of data derived from adult patients admitted to intensive care units (ICUs) for SAE. The current study investigated changes in adult patient characteristics, management, and outcomes of SAE over a 20-year period in 40 ICUs in the greater Paris area. Methods: In this retrospective observational study, admissions to 40 ICUs in the greater Paris area for SAE from January 1, 1997, to December 31, 2016 were analyzed. The primary outcome was the proportion of ICU admissions for SAE during 5-year periods. Secondary outcomes were ICU and hospital mortality, and the use of mechanical ventilation and catecholamine. Multivariate analysis was performed to assess factors associated with ICU mortality. Results: A total of 7049 admissions for SAE were recorded. For each 5-year period, the proportion decreased over time, with SAE accounting for 2.84% of total ICU admissions ( Conclusion: ICU admission for SAE remains uncommon, and the proportion of cases decreased over time. Despite a slight increase in symptom severity during a 20-year period, ICU and hospital mortality decreased. Patients requiring IMV had a higher mortality rate.

Indexed as

EpidemiologyIntensive care unitMechanical ventilationSevere asthma exacerbation

Identifiers

PMID38681794
PMCPMC11043637

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.