Evidence map›Paper›PMID 38681668›Full record

SynthesisFrontiers in aging neuroscience2024

Associations of vitamin D receptor polymorphisms with risk of Alzheimer's disease, Parkinson's disease, and mild cognitive impairment: a systematic review and meta-analysis.

Yanjun Du, Peizhen Geng, Qunqun Chen, Laixi Han, Lu Liu, Maoquan Yang, Mingzhu Tan, Jun Meng, Xiaojuan Sun, Lidan Feng

RetractedAbstract readSystematic ReviewRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Yanjun Du *Department of Encephalopathy, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Peizhen Geng *School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Qunqun ChenDepartment of Rehabilitation, Weifang Brain Hospital, Weifang, Shandong, China.
Laixi HanDepartment of Rehabilitation, Weifang Brain Hospital, Weifang, Shandong, China.
Lu LiuDepartment of Occupational Diseases, Weifang People's Hospital, Weifang, Shandong, China.
Maoquan YangSchool of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.
Mingzhu TanDepartment of Occupational Diseases, Weifang People's Hospital, Weifang, Shandong, China.
Jun MengDepartment of Occupational Diseases, Weifang People's Hospital, Weifang, Shandong, China.
Xiaojuan SunDepartment of Occupational Diseases, Weifang People's Hospital, Weifang, Shandong, China.
Lidan FengDepartment of Rehabilitation, Weifang People's Hospital, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is a lipid soluble steroid hormone, which plays a critical role in the calcium homeostasis, neuronal development, cellular differentiation, and growth by binding to vitamin D receptor (VDR). Associations between VDR gene polymorphism and Alzheimer's disease (AD), Parkinson's disease (PD), and mild cognitive impairment (MCI) risk has been investigated extensively, but the results remain ambiguous. The aim of this study was to comprehensively assess the correlations between four VDR polymorphisms (

Indexed as

Alzheimer’s diseasegene polymorphismmeta-analysismild cognitive impairmentParkinson’s diseasesusceptibilityVDR

Identifiers

PMID38681668
PMCPMC11047136

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.