Evidence map›Paper›PMID 38681378›Full record

ArticleCureus2024

Markedly Delayed Presentation of a Psychotic Disorder 10 Years After the First Onset of Symptoms.

Aoife B O'Reardon, Melissa N Litenski, Melissa Hernandez, Yakov Niyazov, Jadiyer Acosta, Jose Cruz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aoife B O'ReardonDepartment of Psychiatry and Behavioral Health, Herbert Wertheim College of Medicine, Miami, USA.
Melissa N LitenskiDepartment of Psychiatry and Behavioral Health, Herbert Wertheim College of Medicine, Miami, USA.
Melissa HernandezPsychiatry, Mount Sinai Medical Center, Miami Beach, USA.
Yakov NiyazovPsychiatry, Mount Sinai Medical Center, Miami Beach, USA.
Jadiyer AcostaPsychiatry, Mount Sinai Medical Center, Miami Beach, USA.
Jose CruzPsychiatry, Mount Sinai Medical Center, Miami Beach, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia affects 1% of the population, causing chronic debilitating symptoms with largely unknown causes. Structural brain changes and neurochemical alterations are believed to contribute to its etiology. Delayed treatment initiation is a major concern. This case involves a male patient with a decade-long history of psychosis, experiencing isolation, agoraphobia, and paranoid delusions. His situation deteriorated to the point where he lived in a self-imposed physically constraining environment for a year, leading to muscle atrophy and deteriorating health. Delayed help-seeking was driven by insurance concerns, despite prior academic success. Following extensive evaluation, he received the diagnosis of schizophrenia (first episode, severe), requiring multidisciplinary treatment, including medication adjustments and therapy. This case serves as a poignant illustration of a missed opportunity for early intervention, with treatment initiated only after symptoms became severe. Research indicates that early intervention in schizophrenia is crucial, typically leading to improved outcomes, emphasizing its critical importance.

Indexed as

community awarenesslong duration of psychosisschizo-obsessional componentschizophreniatreatment resistance

Identifiers

PMID38681378
PMCPMC11056097

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.