ArticleNeuro-oncology advances
Contemporary trends in the incidence and timing of spinal metastases: A population-based study.
Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Applicability of RECIST1.1, MDACC and SPINO Tumor Response Criteria After Adjuvant Stereotactic Spinal Radiosurgery in Surgically Treated Spinal Metastases.Medicina (Kaunas, Lithuania) · 2026Article
- Predicting Postoperative Complications in Lung Cancer Spinal Metastases: A Nomogram Based on Nutritional, Low Psoas Muscle Index, and Functional Status.Current oncology (Toronto, Ont.) · 2026Article
- The burden of acute care of patients with traumatic vs. non-traumatic SCI: A comparative study.The journal of spinal cord medicine · 2026Article
- Case of salvageSurgical neurology international · 2026Article
- Spinal metastases in geriatric patients: a retrospective single-center comparison of mortality and surgical outcomes following neurosurgical treatment.Frontiers in medicine · 2026Article
- Prediction of survival in patients suffering from spinal metastases: a prospective, multicenter validation study.The oncologist · 2025Article
- Disparities in patient enrollment of spinal oncology clinical trials.Neuro-oncology practice · 2025Article
- A molecular array for 10-second diagnosis of common spinal tumor types with picosecond infrared laser mass spectrometry.Neuro-oncology · 2025Article
- CARBOMETASPINE: protocol for a multicenter, prospective, randomized controlled trial of carbonfiber spinal fixation in metastatic disease.BMC cancer · 2025Article
- Assessing combined effects of risk analysis index-revised (RAI-rev), malnutrition, and anemia on morbidity and mortality after spine surgery for metastatic spinal tumors.Journal of neuro-oncology · 2025Article
- Can Multi-Vertebral CT-Based Finite Element Models Accurately Predict Strains? An In Vitro Validation Study.International journal for numerical methods in biomedical engineering · 2025Article
- The significance of adding posterior decompression to spine stabilization in metastatic spinal surgery: a multicenter prospective study.Scientific reports · 2025Article
- Indocyanine Green as a Marker for Tissue Ischemia in Spinal Tumor Resections and Extended Revisions: A Technical Note.Journal of clinical medicine · 2025Article
- Increased Dose in Spine Stereotactic Radiosurgery for Metastatic Disease: Are We Underestimating the Risks?Medicina (Kaunas, Lithuania) · 2024Article
- Chronic Low Back Pain: History, Symptoms, Pain Mechanisms, and Treatment.Life (Basel, Switzerland) · 2024Review
- Efficacy and Safety of Simultaneous Integrated Boost Followed by Selective Sequential Boost Radiotherapy for Spinal Metastases: A Single-Arm Retrospective Study.Technology in cancer research & treatmentObservational
- Development and validation of the Home time and Overall survival after Metastatic spine tumor surgery Estimator (HOME score).Neuro-oncology advancesArticle
- Evaluation of epidemiological and pathological features of symptomatic spinal metastases in Romania - what could we learn from a retrospective study?Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Synergy of a Low-methionine Diet and Reduced-dose Cisplatinum Eradicates Experimental Lung-cancer Bone Metastases in a Nude-mouse Model.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Spinal metastases are a significant complication of advanced cancer. In this study, we assess temporal trends in the incidence and timing of spinal metastases and examine underlying patient demographics and primary cancer associations. Methods: In this population-based retrospective cohort study, health data from 2007 to 2019 in Ontario, Canada were analyzed ( Results: The age-standardized incidence of spinal metastases increased from 229 to 302 cases per million over the 13-year study period. The average annual percent change (AAPC) in incidence was 2.2% (95% CI: 1.4% to 3.0%) with patients aged ≥85 years demonstrating the largest increase (AAPC 5.2%; 95% CI: 2.3% to 8.3%). Lung cancer had the greatest annual incidence, while prostate cancer had the greatest increase in annual incidence (AAPC 6.5; 95% CI: 4.1% to 9.0%). Lung cancer patients were found to have the highest risk of spine metastasis with 10.3% (95% CI: 10.1% to 10.5%) of patients being diagnosed at 10 years. Gastrointestinal cancer patients were found to have the lowest risk of spine metastasis with 1.0% (95% CI: 0.9% to 1.0%) of patients being diagnosed at 10 years. Conclusions: The incidence of spinal metastases has increased in recent years, particularly among older patients. The incidence and timing vary substantially among different primary cancer types. These findings contribute to the understanding of disease trends and emphasize a growing population of patients who require subspecialty care.
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