ArticleJournal of advanced veterinary and animal research2024
Optimization of solvent and extraction time on secondary metabolite content of mangosteen leaf (
Article in Journal of advanced veterinary and animal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Review
- Evaluation of The Phytochemical Composition and Antimicrobial Properties ofArchives of Razi Institute · 2025Article
- Green-synthesized zinc oxide nanoparticles fromVeterinary world · 2025Article
- Green synthesis of zinc oxide nanoparticles utilizing extract fromJournal of advanced veterinary and animal research · 2024Article
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Authors and funding
8 authors.
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Abstract
Objectives: This research aimed to determine the optimum type of solvent and extraction time to produce secondary metabolites (phenolics, flavonoids, tannins, and antioxidants) from mangosteen leaves ( Materials and Methods: This research used a completely randomized design with a 2 × 5 factorial design with three replications. Factor A used two types of distilled water as a solvent (ordinary distilled water and distilled water heated at 100°C), while Factor B encompassed various extraction times (15, 30, 45, 60, and 75 min). The parameters assessed included total phenolic content (TPC), total flavonoid content (TFC), total tannin content (TTC), and overall antioxidant activity. Results: The TPC, TFC, TTC, and total antioxidant activity all showed a highly significant interaction ( Conclusion: The best solvent and time for mangosteen leaf extract to produce secondary metabolites, which can be candidates for feed additives in poultry, is ordinary distilled water for 45 min. In this research, the phenol content was 81.03%, flavonoids 11.07%, tannins 1.01%, and antioxidants 77.61%.
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