ArticleJournal of clinical tuberculosis and other mycobacterial diseases2024
Implementation of an integrated control programme for neglected tropical diseases of the skin in Ghana: The essential role of the laboratory.
Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- High-dose rifampicin and clarithromycin for 4 weeks versus standard-dose rifampicin and clarithromycin for 8 weeks to treat Buruli ulcer: An open-label, individually randomized, controlled trial in Ghana.PLoS neglected tropical diseases · 2026Trial
- Assessing the acceptability of photographs and medical illustrations in Buruli ulcer health communication among health providers, community volunteers and community members in endemic districts of Ghana.PLoS neglected tropical diseases · 2026Article
- Assessment of the role of Haemophilus ducreyi coinfection on outcomes of Yaws treatment in the southwestern part of Ghana.PLoS neglected tropical diseases · 2026Article
- Seroprevalence and geospatial epidemiology of yaws: Evidence from Ghana.PLoS neglected tropical diseases · 2025Article
- Buruli ulcer: Current landscape, challenges, and future directions.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Dietary variability and micronutrient status of individuals with Yaws infection in Ghana: A case-control study.PloS one · 2025Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Introduction: In this study, we report on findings from approaches used, the outcomes and the lessons learnt from the laboratory support provided for integrated control of skin NTDs including Buruli ulcer (BU), and yaws in seven selected districts in Ghana. Methods: Actions implemented from July 2018 to October 2022 included; training district-level health workers on specimen collection, storage, and transport to laboratories, integrated case searches, continual monitoring and supervision for trained health workers, laboratory confirmation of BU and yaws samples and providing results of the analysed samples to guide decision making. Descriptive analysis of data was performed. Results: A total of 18,683 (including suspected BU 976; suspected yaws 10,995) individuals were screened for BU and yaws. Of 976 suspected BU cases, 16.8% [median (IQR) age 24 (12.0-37.8) years] were confirmed positive by IS2404 PCR; BU mostly presented as ulcers (78.7%); category I (37.2%) and category II (36%). 480 individuals (4.4%) had DPP positive yaws. Multiplex PCR analysis of 75 selected DPP positive cases identified; 7 DPP positive yaws cases as Conclusion: The implementation of integrated diagnostic confirmation for skin NTDs is feasible with provision of timely results within a week. Multiplex diagnostic tools differentiated
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