ArticleJournal of public health research2024
Dysregulation of mood, energy, and social rhythms syndrome (DYMERS): A working hypothesis.
Article in Journal of public health research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Addressing Stress and Rhythm Dysregulation among Health Workers in the Post-Pandemic Context: An Italian Study and a Proposal for a Preventive Psychoeducational Intervention.Clinical practice and epidemiology in mental health : CP & EMH · 2026Article
- High perceived energy: exploring distinct patterns of energetic and cognitive functioning in older adults.Frontiers in psychiatry · 2026Article
- Bipolar disorder in an evolutionary framework: rethinking adaptation, vulnerability, and stigma.Frontiers in psychiatry · 2026Article
- Oral Microbiota Taxa and Pri-miRNA Expression in Bipolar Disorder: A Case-Control Study.Biomolecules · 2025Article
- An Evolutionary Preamble Towards a Multilevel Framework to Understand Adolescent Mental Health: An International Delphi Study.Children (Basel, Switzerland) · 2025Review
- Gender Differences in the Perceived Impact of Major Depressive Disorder on Quality of Life: A Cross-Sectional Population Study.Journal of clinical medicine · 2025Article
- The Inaccuracy of the Mood Disorder Questionnaire for Bipolar Disorder in a Community Sample: From the "DYMERS" Construct Toward a New Instrument for Detecting Vulnerable Conditions.Journal of clinical medicine · 2025Article
- The Breathomics Profile of Volatile Sulfur Compounds in the Bipolar Spectrum, Does It Represent a Potential Tool for Early Diagnosis?Journal of clinical medicine · 2025Article
- An Initial Scoping Review of Dysregulation of Mood, Energy, and Social Rhythms Syndrome (DYMERS) Regarding Burnout in Healthcare Professionals During COVID-19.Journal of clinical medicine · 2025Review
- Promoting healthy aging through intergenerational exchange and digital empowerment: a pilot randomized controlled trial.Frontiers in psychiatry · 2025Article
- Editorial: Neuroimaging in psychiatry 2023: mood disorders.Frontiers in psychiatry · 2025Article
- Adaptive Hyperactivity and Biomarker Exploration: Insights from Elders in the Blue Zone of Sardinia.Journal of clinical medicine · 2024Article
- Are Depressive Symptoms in Obstructive Sleep Apnea Attributable to a Syndrome of Dysregulation of Rhythms and Hyperactivity (DYMERS)?Journal of clinical medicine · 2024Article
- Examining Anxiety and Insomnia in Internship Students and Their Association with Internet Gaming Disorder.Journal of clinical medicine · 2024Article
- Improving Quality of Life in Bipolar Disorders with an Immersive Virtual Reality Remediation Training Randomized Controlled Trial (RCT).Journal of clinical medicine · 2024Article
- Stress, Dysregulation of Rhythms, and Bipolar Disorder: A Challenging Field of Research.Journal of clinical medicine · 2024Article
- Editorial: Reviews in psychiatry 2023: schizophrenia.Frontiers in psychiatry · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A syndrome centered on the dysregulation of behavioral rhythms (DBR) is discussed. Recent pandemic brought to observe: (1) Having a DBR affecting sleep patterns, eating habits, and social interactions, before the lockdown period, was a determinant for depressive episodes during the lockdown; (2) In tighter lockdowns, DBR triggered depressive episodes in bipolar patients; (3) DBR in healthcare workers under pressure was a determinant of burnout; (4) DBR influenced the course of chronic diseases by altering immune responses. In addition, it was found that scoring positive on the Mood Disorder Questionnaire (MDQ) was closely associated with the dysregulation of sleep rhythms. MDQ is a screening tool for bipolar disorder (BD), criticized for detecting too many false positives. Studies showed that positivity to the MDQ implied a severe impairment of quality of life even in people without psychiatric diagnoses. According to this evidence, three different hyperactivation levels could be proposed (from normality to pathology): firstly, an adaptive increase in energy (e.g. athletes performing well); secondly, a DBR determined from the continuous stimulation of stress hormones, with possible positive scores on the MDQ without a diagnosis of bipolar disorder, like in burnout syndromes and, thirdly, hyperactivity during manic episodes. The Dysregulation of Mood, Energy, and Social Rhythms Syndrome (DYMERS), the second level of the scale, is proposed as a working hypothesis. DYMERS is also seen as a vulnerable condition that may evolve in other disorders (including BD) according to the individual susceptibility (including genetic predisposition) and the specific nature/level of the stressor.
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