Evidence map›Paper›PMID 38680606›Full record

ArticleOpen forum infectious diseases2024

All-cause and Infection-attributable Mortality Amongst Adults With Bloodstream Infection-a Population-based Study.

Jonathan Underwood, Rowena Griffiths, David Gillespie, Ashley Akbari, Haroon Ahmed

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. mNGS-Supported Interpretation ofInfection and drug resistance · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Platelets and mortality in bloodstream infection: a multicenter cohort study.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Beyond Human Babesiosis: Prevalence and Association ofOpen forum infectious diseases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan UnderwoodDivision of Infection and Immunity, Cardiff University, Cardiff, UK.ORCID https://orcid.org/0000-0001-6963-2821
Rowena GriffithsPopulation Data Science, Swansea University, Swansea, UK.
David GillespieCentre for Trials Research, Cardiff University School of Medicine, Cardiff, UK.
Ashley AkbariPopulation Data Science, Swansea University, Swansea, UK.ORCID https://orcid.org/0000-0003-0814-0801
Haroon AhmedDivision of Population Medicine, Cardiff University School of Medicine, Cardiff, UK.ORCID https://orcid.org/0000-0002-0634-8548

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bloodstream infections (BSIs) are common, life-threatening infections. However, it remains unclear whether deaths following BSIs are primarily from uncontrolled infection or underlying comorbidities. We aimed to determine the overall mortality, infection-attributable mortality, and causes of death for four leading BSI pathogens. Methods: This retrospective cohort study was conducted within the Secure Anonymized Information Linkage Databank, containing anonymized population-scale electronic health record data for Wales, UK. We included adults with Results: We identified 35 691 adults with BSI (59.6% Conclusions: This population-level study challenges the assumption that most deaths following BSIs are directly attributable to uncontrolled infection, particularly subacutely more than 30 days from BSI. Our findings underscore the need for reevaluating clinical trial design and developing better preventive strategies for BSIs.

Indexed as

bloodstream infectioncause of deathinflammationmortalitysepsis

Identifiers

PMID38680606
PMCPMC11055210

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.