Evidence map›Paper›PMID 38680587›Full record

ArticleAsian journal of urology2024

Transperineal laser ablation of the prostate as a treatment for benign prostatic hyperplasia and prostate cancer: The results of a Delphi consensus project.

Andrea Cocci, Marta Pezzoli, Fernando Bianco, Franco Blefari, Pierluigi Bove, Francois Cornud, Gaetano De Rienzo, Paolo Destefanis, Danilo Di Trapani, Alessandro Giacobbe and 28 more

Abstract read
In one paragraph

Article in Asian journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors.

Andrea CocciDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Marta PezzoliUrology Section, University of Florence, Florence, Italy.
Fernando BiancoUrological Research Network, Miami, FL, USA.
Franco BlefariUrology Section, Prato Hospital, Prato, Italy.
Pierluigi BoveTorvergata Oncoscience Research Centre of Excellence, TOR, Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.
Francois CornudDepartment of Radiology, Hôpital Cochin, Paris Descartes University, Paris, France.
Gaetano De RienzoUrology and Andrology Unit II, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Paolo DestefanisUnit of Urology, Città della Salute e della Scienza Hospital, University of Turin, Turin, Italy.
Danilo Di TrapaniUrology Unit, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, Italy.
Alessandro GiacobbeDepartment of Urology, Humanitas Gradenigo Hospital, Turin, Italy.
Luca GiovanessiUrology Unit, Surgical Department, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
Antonino LaganàDepartement of Urology, "S.Giovanni Evangelista" Hospital, Tivoli, Italy.
Giovanni LughezzaniHumanitas Clinical and Research Center-IRCCS, Department of Urology, Rozzano, Italy.
Guglielmo ManentiDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Rome, Italy.
Gianluca MutoDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Gianluigi PatelliDepartment of Interventional Radiology, Pesenti-Fenaroli Hospital-ASST Bergamo Est, Alzano Lombardo, Italy.
Novello PinziDepartment of Urology, University of Siena, Siena, Italy.
Stefano RegusciSwiss International Prostate Center, Geneva, Switzerland.
Giorgio I RussoDepartment of Urology, University of Catania, Italy.
Juan I M SalamancaDepartment of Urology, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain.
Matteo SalviDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Luigi SilvestriDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Faculty of Pharmacy and Medicine, Urology Unit ICOT, Latina, Italy.
Fabrizio VerweijDepartment of Urology, European Institute of Oncology (IEO) IRCCS, Milan, Italy.
Eric WalserDepartment of Radiology, Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Riccardo G BertoloDepartment of Urology, San Carlo di Nancy Hospital, Rome, Italy.
Valerio IacovelliDepartment of Urology, San Carlo di Nancy Hospital, Rome, Italy.
Alessandro BertacciniDepartment of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Debora MarchioriDepartment of Urology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Hugo DavilaFlorida Healthcare Specialist, Urology and Minimally Invasive Surgery, Florida Cancer Specialist and Research Institute, Vero Beach, FL, USA.
Pasquale DitonnoUrology and Andrology Unit II, Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.
Paolo GonteroDepartment of Urology, Molinette Hospital, University of Torino School of Medicine, Turin, Italy.
Gennaro IapiccaUrology Unit, Santa Rita Clinic, Avellino, Italy.
Theo M De ReijkeDepartment of Urology, Amsterdam University Medical Centers, University of Amsterdam, the Netherlands.
Vito RicapitoDepartment of Urology, Policlinico di Bari, Bari, Italy.
Pierluca PellegriniDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Faculty of Pharmacy and Medicine, Urology Unit ICOT, Latina, Italy.
Andrea MinerviniDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Sergio SerniDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.
Francesco SessaDepartment of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate transperineal laser ablation (TPLA) with Echolaser® (Echolaser® TPLA, Elesta S.p.A., Calenzano, Italy) as a treatment for benign prostatic hyperplasia (BPH) and prostate cancer (PCa) using the Delphi consensus method. Methods: Italian and international experts on BPH and PCa participated in a collaborative consensus project. During two rounds, they expressed their opinions on Echolaser® TPLA for the treatment of BPH and PCa answering online questionnaires on indications, methodology, and potential complications of this technology. Level of agreement or disagreement to reach consensus was set at 75%. If the consensus was not achieved, questions were modified after each round. A final round was performed during an online meeting, in which results were discussed and finalized. Results: Thirty-two out of forty invited experts participated and consensus was reached on all topics. Agreement was achieved on recommending Echolaser® TPLA as a treatment of BPH in patients with ample range of prostate volume, from <40 mL (80%) to >80 mL (80%), comorbidities (100%), antiplatelet or anticoagulant treatment (96%), indwelling catheter (77%), and strong will of preserving ejaculatory function (100%). Majority of respondents agreed that Echolaser® TPLA is a potential option for the treatment of localized PCa (78%) and recommended it for low-risk PCa (90%). During the final round, experts concluded that it can be used for intermediate-risk PCa and it should be proposed as an effective alternative to radical prostatectomy for patients with strong will of avoiding urinary incontinence and sexual dysfunction. Almost all participants agreed that the transperineal approach of this organ-sparing technique is safer than transrectal and transurethral approaches typical of other techniques (97% of agreement among experts). Pre-procedural assessment, technical aspects, post-procedural catheterization, pharmacological therapy, and expected outcomes were discussed, leading to statements and recommendations. Conclusion: Echolaser® TPLA is a safe and effective procedure that treats BPH and localized PCa with satisfactory functional and sexual outcomes.

Indexed as

Benign prostatic hyperplasiaDelphi consensusProstate cancerTransperineal laser ablation

Identifiers

PMID38680587
PMCPMC11053328

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.