Evidence map›Paper›PMID 38680549›Full record

ArticlePractical laboratory medicine2024

Application of a clamshell isothermal nucleic acid amplification analyzer in the detection of lower respiratory tract bacteria.

Guanbin Zhang, Xiaoying Lin, Wenkun Mu, Jun Luo, Yiyuan Xu, Chicheng Song, Jiang Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Practical laboratory medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guanbin ZhangDepartment of Research and Development, Chengdu CapitalBio Medical Laboratory, Chengdu, Sichuan, China.
Xiaoying LinDepartment of Research and Development, Fujian CapitalBio Medical Laboratory, Fuzhou, Fujian, China.
Wenkun MuDepartment of Reagent Technology, CapitalBio Technology (Chengdu), Chengdu, Sichuan, China.
Jun LuoDepartment of Academic Extension, Chengdu CapitalBio Medical Laboratory, Chengdu, Sichuan, China.
Yiyuan XuDepartment of Research and Development, Fujian CapitalBio Medical Laboratory, Fuzhou, Fujian, China.
Chicheng SongDepartment of Instrument Technology, CapitalBio Technology (Chengdu), Chengdu, Sichuan, China.
Jiang LiDepartment of Academic Extension, Chengdu CapitalBio Medical Laboratory, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The clamshell isothermal nucleic acid amplification analyzer RTisochip-S, a next-generation instrument featuring improved structural design, enhanced functional integration, reduced cost, and increased portability, was assessed for its suitability in clinical respiratory pathogens detection. Methods: The certificated detection kit for lower respiratory tract bacteria (LRTB-kit) was applied to evaluate the performance of RTisochip-S via sensitivity, specificity, and repeatability analysis. The clinical specimens, including 51 sputum specimens and 10 bronchoalveolar lavage fluid specimens, were simultaneously detected on both RTisochip-S and a certificated reference instrument (RTisochip-A) to assess the consistency. Results: The results indicated that RTisochip-S fulfills the sensitivity, specificity, and repeatability requirements of the LRTB-Kit, and the results of clinical specimens on the two instruments were consistent. Conclusions: RTisochip-S is satisfying the clinical detection of respiratory pathogens while enhancing portability and compactness, making it more well-suited for point-of-care testing (POCT) applications.

Indexed as

Isothermal amplification technologyPoint-of-care testing instrumentRespiratory pathogen detectionRespiratory tract infection

Identifiers

PMID38680549
PMCPMC11047283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.