Evidence map›Paper›PMID 38680232›Full record

ArticleF1000Research2022

Association of

Michael P Heaton, Gregory P Harhay, Adam S Bassett, Halden J Clark, Jaden M Carlson, Erin E Jobman, Helen R Sadd, Madeline C Pelster, Aspen M Workman, Larry A Kuehn and 6 more

Abstract read
In one paragraph

Article in F1000Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Viruses · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Potential negative effects of genomic selection.Journal of animal science · 2024
    Article
  8. Article
  9. Association ofF1000Research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael P HeatonUSDA, ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA.ORCID 0000-0003-1386-1208
Gregory P HarhayUSDA, ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA.ORCID 0000-0002-0129-6822
Adam S BassettUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Halden J ClarkUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Jaden M CarlsonUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Erin E JobmanUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Helen R SaddUSDA, ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA.
Madeline C PelsterUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Aspen M WorkmanUSDA, ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA.
Larry A KuehnUSDA, ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA.
Theodore S KalbfleischUniversity of Kentucky, Lexington, Kentucky, 40506, USA.ORCID 0000-0002-2370-8189
Heather PiscatelliMatMaCorp, Lincoln, Nebraska, 68507, USA.
Michael CarrieMatMaCorp, Lincoln, Nebraska, 68507, USA.
Greta M KrafsurAnschutz Medical Campus, University of Colorado Denver, Aurora, Colorado, 80045, USA.
Dale M GrotelueschenUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.
Brian L Vander LeyUniversity of Nebraska-Lincoln, Great Plains Veterinary Educational Center, Clay Center, Nebraska, 68933, USA.ORCID 0000-0003-0732-2590

Funding

U.S. Department of Agriculture 5438-32000-033-00D
6 · The paper itself

Abstract

Background: Bovine congestive heart failure (BCHF) has become increasingly prevalent among feedlot cattle in the Western Great Plains of North America with up to 7% mortality in affected herds. BCHF is an untreatable complex condition involving pulmonary hypertension that culminates in right ventricular failure and death. Genes associated with BCHF in feedlot cattle have not been previously identified. Our aim was to search for genomic regions associated with this disease. Methods: A retrospective, matched case-control design with 102 clinical BCHF cases and their unaffected pen mates was used in a genome-wide association study. Paired nominal data from approximately 560,000 filtered single nucleotide polymorphisms (SNPs) were analyzed with McNemar's test. Results: Two independent genomic regions were identified as having the most significant association with BCHF: the arrestin domain-containing protein 3 gene ( Conclusions: Although pathogenic roles for variants in the

Indexed as

ArrestinsCattle DiseasesGenetic Predisposition to DiseaseHeart FailureNFI Transcription FactorsAnimalsCase-Control StudiesCattleGenome-Wide Association StudyPolymorphism, Single NucleotideRetrospective StudiesArrestinsNFI Transcription FactorsARRDC3BovineCongestive Heart FailureGWASNFIA

Identifiers

PMID38680232
PMCPMC11046187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.