Evidence map›Paper›PMID 38680161›Full record

ArticleJournal of aerosol science2024

The BioCascade-VIVAS system for collection and delivery of virus-laden size-fractionated airborne particles.

Sripriya Nannu Shankar, William B Vass, John A Lednicky, Tracey Logan, Rebeccah L Messcher, Arantzazu Eiguren-Fernandez, Stavros Amanatidis, Tara Sabo-Attwood, Chang-Yu Wu

Abstract read
In one paragraph

Article in Journal of aerosol science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Development of a Platform forAerosol science and technology : the journal of the American Association for Aerosol Research · 2026
    Article
  3. Article
  4. Occupational exposure monitoring of airborne respiratory viruses in outpatient medical clinics.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2024
    Article
  5. Concentrating viable airborne pathogens using a virtual impactor with a compact water-based condensation air sampler.Aerosol science and technology : the journal of the American Association for Aerosol Research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sripriya Nannu ShankarDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, FL 32611, USA.
William B VassDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, FL 32611, USA.
John A LednickyDepartment of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA.
Tracey LoganDepartment of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA.
Rebeccah L MesscherDepartment of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA.
Arantzazu Eiguren-FernandezAerosol Dynamics Inc., Berkeley, CA 94710, USA.
Stavros AmanatidisAerosol Dynamics Inc., Berkeley, CA 94710, USA.
Tara Sabo-AttwoodDepartment of Environmental and Global Health, University of Florida, Gainesville, FL 32610, USA.
Chang-Yu WuDepartment of Environmental Engineering Sciences, University of Florida, Gainesville, FL 32611, USA.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Together: Transforming and Translating Discovery to Improve HealthTL1TR001428 · NCATS · UNIVERSITY OF FLORIDA · PI MCCORMACK, WAYNE T. · 2015 to 2023
$3.9M
Biocascade inletR44AI157123 · NIAID · AEROSOL DYNAMICS, INC. · PI EIGUREN FERNANDEZ, ARANTZAZU · 2023 to 2024
$1.2M
New BioCascade System for Investigating the Airborne Transmission Modes of Respiratory VirusesR43AI157123 · NIAID · AEROSOL DYNAMICS, INC. · PI EIGUREN FERNANDEZ, ARANTZAZU · 2021 to 2021
$256k
NCATS NIH HHS TL1 TR001428NCATS NIH HHS UL1 TR001427NIAID NIH HHS R43 AI157123NIAID NIH HHS R44 AI157123
6 · The paper itself

Abstract

The size of virus-laden particles determines whether aerosol or droplet transmission is dominant in the airborne transmission of pathogens. Determining dominant transmission pathways is critical to implementing effective exposure risk mitigation strategies. The aerobiology discipline greatly needs an air sampling system that can collect virus-laden airborne particles, separate them by particle diameter, and deliver them directly onto host cells without inactivating virus or killing cells. We report the use of a testing system that combines a BioAerosol Nebulizing Generator (BANG) to aerosolize Human coronavirus (HCoV)-OC43 (OC43) and an integrated air sampling system comprised of a BioCascade impactor (BC) and Viable Virus Aerosol Sampler (VIVAS), together referred to as BC-VIVAS, to deliver the aerosolized virus directly onto Vero E6 cells. Particles were collected into four stages according to their aerodynamic diameter (Stage 1: >9.43 μm, Stage 2: 3.81-9.43 μm, Stage 3: 1.41-3.81 μm and Stage 4: <1.41 μm). OC43 was detected by reverse-transcription quantitative polymerase chain reaction (RT-qPCR) analyses of samples from all BC-VIVAS stages. The calculated OC43 genome equivalent counts per cm

Indexed as

air samplingbioaerosolsExposure systemparticle sizevirus infectivity

Identifiers

PMID38680161
PMCPMC11044810

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.