Evidence map›Paper›PMID 38680113›Full record

ArticleBJU international2024

Racial disparities in stage at bladder cancer diagnosis in the US Veterans Affairs healthcare system.

Kelly K Bree, Jessica L Janes, Patrick J Hensley, Aditya Srinivasan, Amanda M De Hoedt, Sanjay Das, Stephen J Freedland, Stephen B Williams

Abstract read
In one paragraph

Article in BJU international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kelly K BreeDepartment of Urology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0003-4532-7763
Jessica L JanesDivision of Urology, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Patrick J HensleyDepartment of Urology, University of Kentucky College of Medicine, Lexington, KY, USA.
Aditya SrinivasanDivision of Urology, Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Amanda M De HoedtDivision of Urology, Durham Veterans Affairs Health Care System, Durham, NC, USA.ORCID 0000-0002-3899-7702
Sanjay DasDivision of Urology, Durham Veterans Affairs Health Care System, Durham, NC, USA.
Stephen J FreedlandDivision of Urology, Durham Veterans Affairs Health Care System, Durham, NC, USA.ORCID 0000-0002-8104-6419
Stephen B WilliamsDivision of Urology, Department of Surgery, University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0002-2683-2185

Funding

Patient-Centered Outcomes Research Training in Urologic and Gynecologic Cancers (PCORT UroGynCan)T32CA251072 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Beth Y. Karlan, MARK S. LITWIN · 2020 to 2026
$2.1M
NCI NIH HHS T32 CA251072PCORTU.S. Department of Defense
6 · The paper itself

Abstract

objectiveTo describe patient characteristics and pathological stage at bladder cancer (BCa) diagnosis in a diverse population within a national, equal-access healthcare system.

methodsThis retrospective cohort study identified 15 966 men diagnosed with BCa in the Veterans Affairs (VA) healthcare system from 2000 to 2020. The primary outcome was pathological stage at diagnosis, determined by index transurethral resection of bladder tumour. Logistic regression was used to assess the relationship between race and stage. Competing risk models tested the association between race and BCa-specific mortality with cumulative incidence estimates.

resultsOf 15 966 BCa patients, 12 868 (81%), 1726 (11%), 493 (3%) and 879 (6%) were White, Black, Hispanic and Other race, respectively. Black patients had significantly higher muscle-invasive bladder cancer (MIBC) rates than White patients (35% vs 32%; P = 0.009). In multivariable analysis, the odds of presenting with MIBC did not differ significantly between Black and White patients (odds ratio [OR] 1.10, 95% confidence interval [CI] 0.98-1.22) or between Hispanic patients (OR 0.82, 95% CI 0.67-1.01) and White patients. Compared to White patients, Black patients had a similar risk of BCa-specific mortality (hazard ratio [HR] 0.89, 95% CI 0.75-1.06), whereas Hispanic patients had a lower risk (HR 0.56, 95% CI 0.38-0.82).

conclusionsBlack patients presented with the highest rates of de novo MIBC. However, in a large, equal-access healthcare system, this did not result in a difference in BCa-specific mortality. In contrast, Hispanic patients had lower risks of MIBC and BCa-specific mortality.

Indexed as

Neoplasm StagingUrinary Bladder NeoplasmsAgedAged, 80 and overBlack or African AmericanHealthcare DisparitiesHispanic or LatinoHumansMaleMiddle AgedRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsWhitebladder cancerdisparitiesequal accessmuscle‐invasive bladder cancerrace

Identifiers

PMID38680113
PMCPMC12232451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.