Evidence map›Paper›PMID 38680021›Full record

ArticleBrain and behavior2024

Diabetes and vascular mild cognitive impairment among Chinese ≥50 years: A cross-sectional study with 2020 participants.

Yu Zhang, Wenna Liu, Chen Fu, Xuemei Liu, Xiaobing Hou, Huanmin Niu, Tao Li, Chunyan Guo, Aixun Li, Baoxin Chen and 1 more

Abstract read
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Yu ZhangDepartment of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.ORCID 0000-0003-0668-7694
Wenna LiuClinical Trial Institution, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Chen FuCentral Laboratory, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xuemei LiuCentral Laboratory, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xiaobing HouDepartment of Neurology, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Huanmin NiuDepartment of Neurology, Beijing First Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Tao LiDepartment of Gerontology, Shanxi Traditional Chinese Medicinal Hospital, Taiyuan, China.
Chunyan GuoDepartment of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Aixun LiDepartment of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Baoxin ChenDepartment of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.
Xianglan JinDepartment of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China.

Funding

Brain Science of Traditional Chinese Medicine of Open Project of Key Discipline in 2013, Beijing University of Chinese Medicine 2013-ZDXKKFKT-38National Key R&D Program of China 2018YFC1704303State Administration of Traditional Chinese Medicine of the People's Republic of China 200807011
6 · The paper itself

Abstract

backgroundWith the decline of cognitive function in vascular cognitive impairment, the burden on the family and society will increase. Therefore, early identification of vascular mild cognitive impairment (VaMCI) is crucial. The focus of early identification of VaMCI is on the attention of risk factors. Therefore, this study aimed to investigate the relationship between diabetes and VaMCI among the Chinese, hoping to predict the risk of VaMCI by diabetes and to move the identification of vascular cognitive impairment forward.

methodsWe collected data from seven clinical centers and nine communities in China. All participants were over 50 years of age and had cognitive complaints. We collected basic information of the participants, and cognitive function was professionally assessed by the Montreal Cognitive Assessment scale. Finally, logistic regression analysis was used to analyze the correlation between each factor and VaMCI.

resultsA total of 2020 participants were included, including 1140 participants with VaMCI and 880 participants with normal cognition. In univariate logistic regression analysis, age, heavy smoking, and diabetes had a positive correlation with VaMCI. At the same time, being married, high education, and light smoking had a negative correlation with VaMCI. After correction, only diabetes (OR = 1.04, 95% CI: 1.01-1.09, p = 0.05) had a positive correlation with VaMCI, and high education (OR = 0.60, 95% CI:.45-.81, p = 0.001) had a negative correlation with VaMCI.

conclusionIn our study, we found that diabetes had a positive correlation with VaMCI, and high education had a negative correlation with VaMCI. Therefore, early identification and timely intervention of diabetes may reduce the risk of VaMCI and achieve early prevention of VaMCI.

Indexed as

Cognitive DysfunctionAgedChinaCross-Sectional StudiesDiabetes MellitusEast Asian PeopleFemaleHumansMaleMiddle AgedRisk Factorsdiabeteseducationprotective factorrisk factorvascular mild cognitive impairment

Identifiers

PMID38680021
PMCPMC11056693

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