Evidence map›Paper›PMID 38679995›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2024

Antiproliferative and Apoptotic Effects of Murici (Byrsonima crassifolia (L.) Kunth and verbascifolia (L.) DC) and Taperebá (Spondias mombin L.) Extracts in Human Prostate Cell Line (PC-3).

Thuane Oliveira Do Amaral Muxfeldt Paim, Nayara Frauches Simas, Joel Pimentel Abreu, Lana Rosa, Thuane Passos Barbosa Lima, Anderson Junger Teodoro

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In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thuane Oliveira Do Amaral Muxfeldt PaimLaboratory of Functional Foods, University of State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Nayara Frauches SimasLaboratory of Functional Foods, University of State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Joel Pimentel AbreuLaboratory of Functional Foods, University of State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Lana RosaLaboratory of Functional Foods, University of State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Thuane Passos Barbosa LimaLaboratory of Functional Foods, University of State of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Anderson Junger TeodoroFluminense Federal University, Food and Nutrition Department of Nutrition and Dietetics, Integrated Food and Nutrition Center (CIAN), Rio de Janeiro, Brazil.ORCID 0000-0002-0949-9528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study aimed to evaluate the antiproliferative and apoptotic effects of extracts obtained from the murici (Byrsonima crassifolia (L.) Kunth and verbascifolia (L.) DC) and taperebá (Spondias mombin L.) pulps, on cell proliferation, cell cycle and apoptosis on human prostate cell line (PC-3).

methodsFour extract was produced from the pulps:  murici aqueous extract (MA), taperebá aqueous extract (TA), murici ethanolic extract (ME) and taperebá ethanolic extract (TE). In the present study, the analysis of cell viability, cell cycle and apoptosis analyze were performed using the MTT method and flow cytometry.

resultsThe results showed that murici and taperebá extracts proved to be inhibitors of cell growth, modulation of cell cycle promoters and capable of enhancing the death in prostate carcinoma cells PC-3; suggesting a regulatory effect in prostate cell line, depending on type of extract and dosage used.

conclusionThese results open a series of perspectives on the use of these bioactive extracts in the prevention and treatment of prostate cancer.

Indexed as

ApoptosisCell ProliferationPlant ExtractsProstatic NeoplasmsCell CycleCell SurvivalHumansMalePC-3 CellsTumor Cells, CulturedPlant ExtractsAmazon FruitscancerMuriciprostateTaperebá

Identifiers

PMID38679995
PMCPMC11162719

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.