Evidence map›Paper›PMID 38679899›Full record

Trial reportCurrent eye research2024

Choriocapillaris Perfusion after 8 Weeks of High-Speed Circuit Training in Older Healthy Adults.

Ava-Gaye Simms, Joseph F Signorile, Gustavo Rosa Gameiro, Abdulrahman Mamoon Allaf, Jianhua Wang, Hong Jiang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Current eye research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Retinal Neurovascular Signatures in Parkinson's Disease.Investigative ophthalmology & visual science · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ava-Gaye SimmsBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Joseph F SignorileDepartment of Kinesiology and Sports Sciences, University of Miami, Coral Gables, FL, USA.
Gustavo Rosa GameiroBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Abdulrahman Mamoon AllafUniversity of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0003-0404-5890
Jianhua WangBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Hong JiangBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Novel Biomarkers of Small Vessel Contributions to Vascular Cognitive Impairment and Dementia (VCID)R01NS111115 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A, WANG, JIANHUA · 2019 to 2023
$3.7M
NEI NIH HHS P30 EY014801NINDS NIH HHS R01 NS111115
6 · The paper itself

Abstract

purposeThe aim of this study was to examine the impact of an 8-week high-speed circuit resistance training program (HSCT) on choriocapillaris density (CCD) in healthy older adults.

methodsEighteen cognitively normal older adults were enrolled and randomly assigned to either the HSCT or the control group (CON). The HSCT group was comprised of 11 participants who trained three times a week for eight weeks, while the CON group consisted of 7 participants who did not engage in formal training. Optical coherence tomography angiography (OCTA) was employed to image both eyes of each subject at baseline and at the 8-week follow-up. The choriocapillaris density (CCD) of 2.5 mm in diameter centered on the fovea was measured.

resultsThe average age of the HSCT group was 70.3 ± 5.7 years, which was not different from the CON group (average age: 71.6 ± 5.2 years,

conclusionCCD appeared to remain stable after 8 weeks of HSCT in healthy older individuals, possibly due to autoregulation. Further research with extended training may be necessary to verify these findings.

Indexed as

ChoroidTomography, Optical CoherenceAgedCapillariesFemaleFluorescein AngiographyFollow-Up StudiesHealthy VolunteersHumansMaleRegional Blood FlowResistance TrainingAgingchoriocapillarishigh-speed circuit trainingoptical coherence tomography angiographyvascular perfusion

Identifiers

PMID38679899
PMCPMC11254566

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.