Evidence map›Paper›PMID 38679660›Full record

ArticleAnnals of biomedical engineering2024

In Vitro and In Silico Characterization of the Aggregation of Thrombi on Textured Ventricular Cannula.

Wenxuan He, Abhishek Karmakar, Junhyuk Kang, Grant Rowlands, Samuel Schirmacher, Rodrigo Méndez-Rojano, James Antaki

Abstract read
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In one paragraph

Article in Annals of biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenxuan HeSibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA.
Abhishek KarmakarMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA.
Junhyuk KangSibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, 14853, USA.
Grant RowlandsMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA.
Samuel SchirmacherMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA.
Rodrigo Méndez-RojanoMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA.
James AntakiMeinig School of Biomedical Engineering, Cornell University, Ithaca, NY, 14853, USA. antaki@cornell.edu.ORCID http://orcid.org/0000-0002-5430-7353

Funding

Multiscale Model of Thrombosis in Artificial CirculationR01HL089456 · NHLBI · CORNELL UNIVERSITY · PI ANTAKI, JAMES F., BUTCHER, JONATHAN TALBOT · 2009 to 2024
$8.5M
NHLBI NIH HHS HL089456
6 · The paper itself

Abstract

The unacceptably high stroke rate associated with HeartMate 3 ventricular assist device (VAD) without signs of adherent pump thrombosis is hypothesized to be the result of the emboli produced by the inflow cannula, that are ingested and ejected from the pump. This in vitro and numerical study aimed to emulate the surface features and supraphysiological shear of a ventricular cannula to provide insight into their effect on thrombogenesis. Human whole blood was perfused at calibrated flow rates in a microfluidic channel to achieve shear rates 1000-7500 s

Indexed as

CannulaComputer SimulationThrombosisBlood PlateletsHeart-Assist DevicesHumansModels, CardiovascularCannulaCFDLVADMicrofluidicsPlatelet depositionThrombosis

Identifiers

PMID38679660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.