Evidence map›Paper›PMID 38679329›Full record

ArticleThe Journal of biological chemistry2024

Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor.

Nataša Tomašević, Fabiola Susanna Emser, Edin Muratspahić, Jasmin Gattringer, Simon Hasinger, Roland Hellinger, Peter Keov, Manuel Felkl, Jürg Gertsch, Christian F W Becker and 1 more

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Advances in Cyclic Peptides Targeting G Protein-Coupled Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nataša TomaševićCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Fabiola Susanna EmserCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Edin MuratspahićCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Jasmin GattringerCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Simon HasingerCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Roland HellingerCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria.
Peter KeovMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Manuel FelklInstitute of Biological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Jürg GertschInstitute of Biochemistry and Molecular Medicine, University of Bern, Bern, Switzerland.
Christian F W BeckerInstitute of Biological Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria.
Christian W GruberCenter for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria. Electronic address: christian.w.gruber@meduniwien.ac.at.

Funding

Austrian Science Fund FWF P 32109
6 · The paper itself

Abstract

The cannabinoid type 2 receptor (CB

Indexed as

Receptor, Cannabinoid, CB2CyclotidesDrug DiscoveryHEK293 CellsHumansLigandsCNR2 protein, humanCyclotidesLigandsReceptor, Cannabinoid, CB2allosteric modulatorcannabinoid type 2 receptorG protein-coupled receptorpeptideplant

Identifiers

PMID38679329
PMCPMC11154713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.