Evidence map›Paper›PMID 38678685›Full record

ArticleJournal of psychiatric research2024

Deployment-related toxic exposures are associated with worsening mental and physical health after military service: Results from a self-report screening of veterans deployed after 9/11.

Kyle J Bourassa, H Ryan Wagner, Tate F Halverson, Allison E Ashley-Koch, Jean Beckham, Melanie E Garrett, VA Mid Atlantic MIRECC Workgroup, Nathan A Kimbrel, Jennifer C Naylor

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Accelerated biological aging and midlife frailty among U.S. military veterans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kyle J BourassaVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA; Geriatric Research, Education, and Clinical Center, Durham Veteran Affairs (VA) Health Care System, USA; Center for the Study of Aging and Human Development, Duke University Medical Center, USA. Electronic address: kyle.bourassa@duke.edu.
H Ryan WagnerVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, USA.
Tate F HalversonVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA.
Allison E Ashley-KochDuke Molecular Physiology Institute, Duke University Medical Center, USA.
Jean BeckhamVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, USA.
Melanie E GarrettDuke Molecular Physiology Institute, Duke University Medical Center, USA.
VA Mid Atlantic MIRECC WorkgroupVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA.
Nathan A KimbrelVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, USA; VA Health Services Research and Development Center of Innovation to Accelerate Discovery and Practice Transformation, Durham VA Health Care System, USA.
Jennifer C NaylorVA Mid-Atlantic Mental Illness Research, Education and Clinical Center, Durham VA Health Care System, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, USA.

Funding

Posttraumatic Stress Disorder, Accelerated Biological Aging, and Veteran HealthIK2CX002694 · VA · DURHAM VA MEDICAL CENTER · PI Kyle J. Bourassa · 2023 to 2027
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A Brief Intervention to Reduce Nonsuicidal Self-Injury and Improve Functioning in VeteransIK2RX004803 · VA · DURHAM VA MEDICAL CENTER · PI HALVERSON, TATE F · 2024 to 2025
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CSR&D Research Career Scientist AwardIK6BX003777 · VA · DURHAM VA MEDICAL CENTER · PI BECKHAM, JEAN C. · 2017 to 2023
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BLRD VA IK6 BX003777CSRD VA IK2 CX002694CSRD VA IK6 CX002767RRD VA IK2 RX004803
6 · The paper itself

Abstract

Exposure to toxins-such as heavy metals and air pollution-can result in poor health and wellbeing. Recent scientific and media attention has highlighted negative health outcomes associated with toxic exposures for U.S. military personnel deployed overseas. Despite established health risks, less empirical work has examined whether deployment-related toxic exposures are associated with declines in mental and physical health after leaving military service, particularly among the most recent cohort of veterans deployed after September 11, 2001. Using data from 659 U.S. veterans in the VISN 6 MIRECC Post-Deployment Mental Health Study, we tested whether self-reported toxic exposures were associated with poorer mental and physical health. At baseline, veterans who reported more toxic exposures also reported more mental health, β = 0.14, 95% CI [0.04, 0.23], p = 0.004, and physical health symptoms, β = 0.21, 95% CI [0.11, 0.30], p < 0.001. Over the next ten years, veterans reporting more toxic exposures also had greater increases in mental health symptoms, β = 0.23, 95% CI [0.15, 0.31], p < 0.001, physical health symptoms, β = 0.22, 95% CI [0.14, 0.30], p < 0.001, and chronic disease diagnoses, β = 0.15, 95% CI [0.07, 0.23], p < 0.001. These associations accounted for demographic and military covariates, including combat exposure. Our findings suggest that toxic exposures are associated with worsening mental and physical health after military service, and this recent cohort of veterans will have increased need for mental health and medical care as they age into midlife and older age.

Indexed as

Self ReportVeteransAdultFemaleHealth StatusHumansMaleMental HealthMiddle AgedMilitary DeploymentMilitary PersonnelSeptember 11 Terrorist AttacksUnited StatesChronic diseasesHealthMental healthToxic exposureVeteran status

Identifiers

PMID38678685
PMCPMC11102311

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.