Evidence map›Paper›PMID 38678241›Full record

Trial reportJournal of neuroengineering and rehabilitation2024

Vertical locomotion improves horizontal locomotion: effects of climbing on gait and other mobility aspects in Parkinson's disease. A secondary analysis from a randomized controlled trial.

Agnes Langer, Clint Hansen, Dominik Roth, Agnes Santer, Anna Flotz, Jakob Gruber, Laurenz Wizany, Sebastian Hasenauer, Rochus Pokan, Peter Dabnichki and 8 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04569981 (Climb up, Heads up), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04569981 nacompletednot on this map

Climb up, Heads up: Sport Climbing With Parkinson's Disease

TypeinterventionalSponsorMedical University of ViennaRan2018 to 2019Enrolled48ConditionsParkinson DiseaseArmsClimbing, Unsupervised activity group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Agnes LangerDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Clint HansenDepartment of Neurology, University Hospital Schleswig-Holstein and Kiel University, 24105, Kiel, Germany.
Dominik RothDepartment of Emergency Medicine, Medical University of Vienna, 1090, Vienna, Austria.
Agnes SanterDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Anna FlotzDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Jakob GruberDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Laurenz WizanyDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Sebastian HasenauerDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Rochus PokanDepartment of Sport Physiology, Institute of Sports Sciences, University of Vienna, 1090, Vienna, Austria.
Peter DabnichkiSchool of Engineering, RMIT University, 3000, Melbourne, VIC, Australia.
Marco TrevenDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Sarah ZimmelDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Michaela SchmoegerDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Ulrike WillingerDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Lucia GassnerDepartment of Sport Physiology, Institute of Sports Sciences, University of Vienna, 1090, Vienna, Austria.
Christof BrückeDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria.
Walter MaetzlerDepartment of Neurology, University Hospital Schleswig-Holstein and Kiel University, 24105, Kiel, Germany.
Heidemarie ZachDepartment of Neurology, Medical University of Vienna, Waehringerstrasse 18-21, 1090, Vienna, Austria. heidemarie.zach@meduniwien.ac.at.
Medical University of Vienna · ATUniversity Hospital Schleswig-Holstein · DEUniversity of Vienna · ATRMIT University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the Climb Up! Head Up! trial, we showed that sport climbing reduces bradykinesia, tremor, and rigidity in mildly to moderately affected participants with Parkinson's disease. This secondary analysis aimed to evaluate the effects of sport climbing on gait and functional mobility in this cohort.

methodsClimb Up! Head Up! was a 1:1 randomized controlled trial. Forty-eight PD participants (Hoehn and Yahr stage 2-3) either participated in a 12-week, 90-min-per-week sport climbing course (intervention group) or were engaged in regular unsupervised physical activity (control group). Relevant outcome measures for this analysis were extracted from six inertial measurement units placed on the extremities, chest, and lower back, that were worn during supervised gait and functional mobility assessments before and after the intervention. Assessments included normal and fast walking, dual-tasking walking, Timed Up and Go test, Instrumented Stand and Walk test, and Five Times Sit to Stand test.

resultsCompared to baseline, climbing improved gait speed during normal walking by 0.09 m/s (p = 0.005) and during fast walking by 0.1 m/s. Climbing also reduced the time spent in the stance phase during fast walking by 0.03 s. Climbing improved the walking speed in the 7-m- Timed Up and Go test by 0.1 m/s (p < 0.001) and the turning speed by 0.39 s (p = 0.052), the speed in the Instrumented Stand and Walk test by 0.1 m/s (p < 0.001), and the speed in the Five Times Sit to Stand test by 2.5 s (p = 0.014). There was no effect of sport climbing on gait speed or gait variables during dual-task walking.

conclusionsSport climbing improves gait speed during normal and fast walking, as well as functional mobility in people with Parkinson's disease. Trial registration This study was registered within the U.S. National Library of Medicine (No: NCT04569981, date of registration September 30th, 2020).

Indexed as

GaitParkinson DiseaseAgedExercise TherapyFemaleHumansLocomotionMaleMiddle AgedExerciseGaitMobilityParkinson’s diseaseSport climbing

Identifiers

PMID38678241
PMCPMC11055236
OpenAlexW4395691344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.