Evidence map›Paper›PMID 38678216›Full record

Trial reportAddiction science & clinical practice2024

Hospital admissions among patients with Comorbid Substance Use disorders: a secondary analysis of predictors from the NavSTAR Trial.

Courtney D Nordeck, Sharon M Kelly, Robert P Schwartz, Shannon G Mitchell, Christopher Welsh, Kevin E O'Grady, Jan Gryczynski

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction science & clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02599818 (Navigation Services to Avoid Rehospitalization), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02599818 nacompletednot on this map

Navigation Services to Avoid Rehospitalization (NavSTAR) Among Substance Users

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2016 to 2019Enrolled400ConditionsOpioid-use Disorder, Cocaine Use Disorder, Alcohol Use DisorderArmsNavSTAR
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Courtney D NordeckFriends Research Institute, 1040 Park Avenue #103, Baltimore, MD, USA, 21201. cnordeck@friendsresearch.org.ORCID 0000-0002-3564-9139
Sharon M KellyJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Robert P SchwartzFriends Research Institute, 1040 Park Avenue #103, Baltimore, MD, USA, 21201.
Shannon G MitchellFriends Research Institute, 1040 Park Avenue #103, Baltimore, MD, USA, 21201.
Christopher WelshUniversity of Maryland School of Medicine, Baltimore, MD, USA.
Kevin E O'GradyUniversity of Maryland, College Park, Baltimore, MD, USA.
Jan GryczynskiFriends Research Institute, 1040 Park Avenue #103, Baltimore, MD, USA, 21201.
Friends Research Institute · USUniversity of Maryland, Baltimore · USJohns Hopkins University · US

Funding

NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
Navigation Services to Avoid Rehospitalization (NavSTAR) among substance abusersR01DA037942 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI GRYCZYNSKI, JAN · 2015 to 2018
$2.4M
NIDA NIH HHS R01DA037942NIDA NIH HHS T32 DA007292NIDA NIH HHS T32DA007292
6 · The paper itself

Abstract

backgroundIndividuals with substance use disorders (SUDs) frequently use acute hospital services. The Navigation Services to Avoid Rehospitalization (NavSTAR) trial found that a patient navigation intervention for hospitalized patients with comorbid SUDs reduced subsequent inpatient admissions compared to treatment-as-usual (TAU).

methodsThis secondary analysis extends previous findings from the NavSTAR trial by examining whether selected patient characteristics independently predicted hospital service utilization and moderated the effect of the NavSTAR intervention. Participants were 400 medical/surgical hospital patients with comorbid SUDs. We analyzed 30- and 90-day inpatient readmissions (one or more readmissions) and cumulative incidence of inpatient admissions through 12 months using multivariable logistic and negative binomial regression, respectively.

resultsConsistent with primary findings and controlling for patient factors, NavSTAR participants were less likely than TAU participants to be readmitted within 30 (P = 0.001) and 90 (P = 0.03) days and had fewer total readmissions over 12 months (P = 0.008). Hospitalization in the previous year (P < 0.001) was associated with cumulative readmissions over 12 months, whereas Medicaid insurance (P = 0.03) and index diagnoses of infection (P = 0.001) and injuries, poisonings, or procedural complications (P = 0.004) were associated with fewer readmissions. None of the selected covariates moderated the effect of the NavSTAR intervention.

conclusionsPrevious findings showed that patient navigation could reduce repeat hospital admissions among patients with comorbid SUDs. Several patient factors were independently associated with readmission. Future research should investigate risk factors for hospital readmission among patients with comorbid SUDs to optimize interventions.

trial registrationNIH ClinicalTrials.gov NCT02599818, Registered November 9, 2015 https://classic. CLINICALTRIALS: gov/ct2/show/NCT02599818 .

Indexed as

ComorbidityPatient ReadmissionSubstance-Related DisordersAdultFemaleHospitalizationHumansMaleMiddle AgedPatient NavigationUnited StatesHealthcare utilizationHospitalizationOpioid use disorderPatient navigationSubstance use disorder

Identifiers

PMID38678216
PMCPMC11056040
OpenAlexW4395958437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.