Evidence map›Paper›PMID 38678215›Full record

ArticleBMC cardiovascular disorders2024

Diagnostic value of LGE and T1 mapping in multiple myeloma patients'heart.

Qian Cui, Jing Yu, Xihong Ge, Guangfeng Gao, Yang Liu, Qiang He, Wen Shen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian CuiThe First Central Clinical School, Tianjin Medical University, Tianjin, China.
Jing YuDepartment of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, No.24 Fukang Road, Tianjin, 300192, China.
Xihong GeDepartment of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, No.24 Fukang Road, Tianjin, 300192, China.
Guangfeng GaoDepartment of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, No.24 Fukang Road, Tianjin, 300192, China.
Yang LiuDepartment of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, No.24 Fukang Road, Tianjin, 300192, China.
Qiang HeDepartment of Cardiology, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China.
Wen ShenThe First Central Clinical School, Tianjin Medical University, Tianjin, China. shenwen66happy@126.com.

Funding

Tianjin Health Commission Science and Technology Key Project ZD20002Tianjin Health Commission Science and Technology Talent Cultivation Project RC20184
6 · The paper itself

Abstract

backgroundUnidentified heart failure occurs in patients with multiple myeloma when their heart was involved. CMR with late gadolinium enhancement (LGE) and T1 mapping can identify myocardial amyloid infiltrations. PURPOSE: To explore the role of CMR with late gadolinium enhancement (LGE) and T1 mapping for detection of multiple myeloma patients'heart. MATERIAL AND

methodsA total of 16 MM patients with above underwent CMR (3.0-T) with T1 mapping (pre-contrast and post-contrast) and LGE imaging. In addition, 26 patients with non-obstructive hypertrophic cardiomyopathy and 26 healthy volunteers were compared to age- and sex-matched healthy controls without a history of cardiac disease, diabetes mellitus, or normal in CMR. All statistical analyses were performed using the statistical software GraphPad Prism. The measurement data were represented by median (X) and single sample T test was adopted. Enumeration data were represented by examples and Chi-tested was adopted. All tests were two-sided, and P values < 0.05 were considered statistically significant.

resultsIn MM group, LVEF was lower than healthy controls and higher than that of non-obstructive hypertrophic cardiomyopathy group, but without statistically significant difference (%: 49.1 ± 17.5 vs. 55.6 ± 10.3, 40.4 ± 15.6, all P > 0.05). Pre-contrast T1 values of MM group were obviously higher than those of healthy controls and non-obstructive hypertrophic cardiomyopathy group (ms:1462.0 ± 71.3vs. 1269.3 ± 42.3, 1324.0 ± 45.1, all P < 0.05). 16 cases (100%) in MM group all had LGE.

conclusionLGE joint T1 mapping wider clinical use techniques and follow-up the patients'disease severity.

Indexed as

Cardiomyopathy, HypertrophicContrast MediaMagnetic Resonance Imaging, CineMultiple MyelomaPredictive Value of TestsStroke VolumeVentricular Function, LeftAdultAgedCase-Control StudiesFemaleHeart FailureHumansMaleMiddle AgedMyocardiumContrast MediaCardiovascular magnetic resonanceHeart failureLate gadolinium enhancementMultiple myelomaT1 mapping

Identifiers

PMID38678215
PMCPMC11055279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.