Evidence map›Paper›PMID 38677585›Full record

ReviewThe journal of allergy and clinical immunology. In practice2024

Prevention of IgE-Mediated Food Allergy: Emerging Strategies Through Maternal and Neonatal Interventions.

Katherine Herman, Helen A Brough, Jennifer Pier, Carina Venter, Kirsi M Järvinen

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of allergy and clinical immunology. In practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Novel approaches to prevent or cure allergic diseases.Current opinion in immunology · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Katherine HermanDepartment of Pediatrics, Division of Pediatric Allergy and Immunology, Center for Food Allergy, University of Rochester Medical Center, Rochester, NY.
Helen A BroughEvelina London Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, Children's Allergy Service. King's College London, Pediatric Allergy Group, Department of Women and Children's Health, School of Life Course Sciences, London, UK.
Jennifer PierDepartment of Pediatrics, Division of Pediatric Allergy and Immunology, Center for Food Allergy, University of Rochester Medical Center, Rochester, NY.
Carina VenterSection of Pediatric Allergy and Immunology, Children's Hospital Colorado/University of Colorado, Denver, Colo.
Kirsi M JärvinenDepartment of Pediatrics, Division of Pediatric Allergy and Immunology, Center for Food Allergy, University of Rochester Medical Center, Rochester, NY. Electronic address: Kirsi_Jarvinen-Seppo@urmc.rochester.edu.
University of Rochester Medical Center · USChildren's Hospital Colorado · USGuy's and St Thomas' NHS Foundation Trust · GB

Funding

Role of Skin Barrier and Immune Alterations in Allergic SensitizationU19AI175113 · NIAID · UNIVERSITY OF ROCHESTER · PI Kirsi Jarvinen-Seppo · 2023 to 2026
$7.0M
Detection of Food Allergens in Human MilkR03AI151965 · NIAID · UNIVERSITY OF ROCHESTER · PI SEPPO, ANTTI · 2020 to 2021
$154k
NIAID NIH HHS R03 AI151965NIAID NIH HHS U19 AI175113
6 · The paper itself

Abstract

Whereas the early introduction of highly allergenic foods has been shown to be effective at preventing the onset of food allergy (FA) in high-risk infants, sensitization to food antigens can occur prior to complementary food introduction, and thus, additional earlier FA prevention strategies are urgently needed. Currently, aside from early introduction of peanut and egg, no therapies are strongly recommended by international professional allergy societies for the primary prevention of FA. This review focuses on maternal- and neonatal-directed interventions that are being actively investigated and developed, including maternal dietary factors and supplementation, specific elimination diets, breastfeeding, cow's milk formula supplementation, microbiome manipulations, bacterial lysate therapy, and skin barrier therapies. Evaluating how these factors and various prenatal/early life environmental exposures may impact the development of FA is crucial for accurately counseling caregivers in the prevention of FA.

Indexed as

Food HypersensitivityImmunoglobulin EAllergensAnimalsBreast FeedingFemaleHumansInfantInfant, NewbornPregnancyAllergensImmunoglobulin EAtopic dermatitisBreastfeedingFood allergyFood antigenNutritionPreventionSkin barrier function

Identifiers

PMID38677585
PMCPMC11420814
OpenAlexW4395469197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.