Evidence map›Paper›PMID 38677544›Full record

ArticleJournal of advanced research2025

Application of atmospheric cold plasma for zearalenone detoxification in cereals: Kinetics, mechanisms, and cytotoxicity analysis.

Mengjie Liu, Junxia Feng, Yongqin Fan, Xudong Yang, Ruike Chen, Cui Xu, Hangbo Xu, Dongjie Cui, Ruixue Wang, Zhen Jiao and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mengjie LiuZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China.
Junxia FengHuadu District People's Hospital of Guangzhou, Guangzhou 510800, China.
Yongqin FanZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China.
Xudong YangZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China.
Ruike ChenSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou 450001, China.
Cui XuZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China.
Hangbo XuZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China.
Dongjie CuiZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China.
Ruixue WangCollege of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China.
Zhen JiaoZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China. Electronic address: jiaozhen@zzu.edu.cn.
Ruonan MaZhengzhou Research Base, State Key Laboratory of Cotton Biology, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Ion-beam Green Agricultural Bioengineering, Zhengzhou University, Zhengzhou 450052, China; Sanya Institute, Zhengzhou University, Zhengzhou 450001, China. Electronic address: maruonan@zzu.edu.cn.
Zhengzhou University · CNSanya University · CNBeijing University of Chemical Technology · CNTwelfth Guangzhou City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionZearalenone (ZEN) is one of the most widely contaminated mycotoxins in world, posing a severe threat to human and animal health. Atmospheric cold plasma (ACP) holds great penitential in mycotoxin degradation.

objectivesThis study aimed to investigate the degradation efficiency and mechanisms of ACP on ZEN as well as the cytotoxicity of ZEN degradation products by ACP. Additionally, this study also investigated the degradation efficiency of ACP on ZEN in cereals and its effect on cereal quality.

methodsThe degradation efficiency and products of ZEN by ACP was analyzed by HPLC and LC-MS/MS. The human normal liver cells and mice were employed to assess the cytotoxicity of ZEN degradation products. The ZEN artificially contaminated cereals were used to evaluate the feasibility of ACP detoxification in cereals.

resultsThe results showed that the degradation rate of ZEN was 96.18 % after 30-W ACP treatment for 180 s. The degradation rate was dependent on the discharge power, and treatment time and distance. Four major ZEN degradation products were produced after ACP treatment due to the oxidative destruction of CC double bond, namely C

conclusionsThis study demonstrates that ACP could efficiently degrade ZEN in cereals and its cytotoxicity was significantly reduced. Therefore, ACP is a promising effective method for ZEN detoxification in cereals to ensure human and animal health. Future study needs to develop large-scale ACP device with high degradation efficiency.

Indexed as

Edible GrainPlasma GasesZearalenoneAnimalsCell SurvivalFood ContaminationHumansInactivation, MetabolicKineticsMiceTandem Mass SpectrometryPlasma GasesZearalenoneAtmospheric cold plasmaCereals qualityDegradation productsDetoxificationMycotoxinsReactive oxygen and nitrogen species

Identifiers

PMID38677544
PMCPMC11976565
OpenAlexW4395677743

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.