Evidence map›Paper›PMID 38677322›Full record

ArticleJornal de pediatria

Predictive value of PAR and PNI for the acute complicated course of pediatric acute hematogenous osteomyelitis.

Chaochen Zhao, Zhiye Guan, Qizhi Jiang, Wangqiang Wu, Xiaodong Wang

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Article in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chaochen ZhaoChildren's Hospital of Soochow University, Department of Orthopaedics, Suzhou, Jiangsu Province, China.
Zhiye GuanShanghai Jiao Tong University, School of Medicine, Shanghai Children's Hospital, Department of Orthopaedics, Shanghai, China.
Qizhi JiangChildren's Hospital of Soochow University, Department of Orthopaedics, Suzhou, Jiangsu Province, China.
Wangqiang WuChildren's Hospital of Soochow University, Department of Orthopaedics, Suzhou, Jiangsu Province, China.
Xiaodong WangChildren's Hospital of Soochow University, Department of Orthopaedics, Suzhou, Jiangsu Province, China. Electronic address: wangxd@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePlatelet to albumin ratio (PAR) and prognostic nutritional index (PNI) are potential indicators for evaluating nutritional and inflammatory status. This study aimed to examine the relationship between PAR and PNI and the acute complicated course of acute hematogenous osteomyelitis (AHO).

methodsAHO patients were divided into the simple course group and the acute complicated course group. The patient's gender, age, site of infection, body temperature, laboratory results, and pathogen culture results were collected and compared. Multivariate logistic regression analysis was used to determine the independent risk factors of the acute complicated course group. The receiver operating characteristic curve was applied to determine the optimal cut-off value.

resultsIn total, 101 AHO patients with a median age of 7.58 years were included. There were 63 cases (62.4 %) in the simple course group and 38 cases (37.6 %) in the complicated course group. Binary logistic regression analysis revealed that PAR and PNI were independent risk factors for predicting the acute complicated course of AHO (p = 0.004 and p < 0.001, respectively). Receiver operating characteristic curve analysis demonstrated that the combination of PAR and PNI had an area under the curve of 0.777 (95 % CI: 0.680-0.873, p < 0.001) with a cut-off value of 0.51.

conclusionsThe incidence of acute complicated courses was significantly higher in patients with high PAR and low PNI. A combined factor greater than 0.51, derived from PAR and PNI measurements within 24 h of admission, may be useful for predicting AHO patients who are likely to develop severe disease.

Indexed as

OsteomyelitisPredictive Value of TestsAcute DiseaseAdolescentChildChild, PreschoolFemaleHumansInfantLogistic ModelsMaleNutritional StatusNutrition AssessmentPlatelet CountPrognosisRetrospective StudiesSerum AlbuminAcute hematogenous osteomyelitisComplicationPlatelet to albumin ratioPrognostic nutritional index

Identifiers

PMID38677322
PMCPMC11361888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.